1. Anti-infection
  2. Bacterial

Tebipenem (Synonyms: LJC 11036)

Cat. No.: HY-A0076 Purity: >98.0%
Handling Instructions

Tebipenem is an orally available carbapenem antibiotic, shows broad-spectrum activity against Gram-positive and -negative bacteria, except for Pseudomonas aeruginosa.

For research use only. We do not sell to patients.

Tebipenem Chemical Structure

Tebipenem Chemical Structure

CAS No. : 161715-21-5

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 198 In-stock
Estimated Time of Arrival: December 31
5 mg USD 180 In-stock
Estimated Time of Arrival: December 31
10 mg USD 336 In-stock
Estimated Time of Arrival: December 31
50 mg USD 900 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

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Other Forms of Tebipenem:

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Tebipenem is an orally available carbapenem antibiotic, shows broad-spectrum activity against Gram-positive and -negative bacteria, except for Pseudomonas aeruginosa.

In Vitro

Tebipenem exhibits slow tight-binding inhibition at low micromolar concentrations versus the chromogenic substrate nitrocefin, and apparent Km and kcat values of 0.8 μM and 0.03 min-1, respectively[1]. Tebipenem shows potent activity against B. pseudomallei, with MIC50 and MIC90 values of both 2 mg/L[2]. Tebipenem shows good activity against S. pneumoniae, with the MIC range of ≤0.25 μg/mL in all of the S. pneumoniae isolates[3].

Solvent & Solubility
In Vitro: 

DMSO : ≥ 45 mg/mL (117.34 mM)

H2O : 6.2 mg/mL (16.17 mM; Need ultrasonic and warming)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6076 mL 13.0381 mL 26.0763 mL
5 mM 0.5215 mL 2.6076 mL 5.2153 mL
10 mM 0.2608 mL 1.3038 mL 2.6076 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

383.49

Formula

C₁₆H₂₁N₃O₄S₂

CAS No.

161715-21-5

SMILES

O=C(C(N1C2=O)=C(SC3CN(C4=NCCS4)C3)[[email protected]](C)[[email protected]]1([H])[[email protected]@]2([H])[[email protected]](O)C)O

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Purity: >98.0%

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This equation is commonly abbreviated as: C1V1 = C2V2

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Product Name:
Tebipenem
Cat. No.:
HY-A0076
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Tebipenem

Cat. No.: HY-A0076