2. Neuronal Signaling
  3. Amyloid-β
  4. β-Amyloid (1-15)

β-Amyloid (1-15)  (Synonyms: Amyloid β-Protein (1-15))

製品番号: HY-P1046
COA 取扱説明書 Technical Support

β-Amyloid (1-15) is a fragment of β-Amyloid peptide. Beta-amyloid is a peptide that forms amyloid plaques in the brains of Alzheimer's disease (AD) patients.

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β-Amyloid (1-15)

β-Amyloid (1-15) 構造式

CAS 番号 : 183745-81-5

容量 価格（税別） 在庫状況 数量
1 mg $50 在庫あり
5 mg $125 お問い合わせ
10 mg $200 お問い合わせ
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β-Amyloid (1-15) 関連抗体

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製品説明

β-Amyloid (1-15) is a fragment of β-Amyloid peptide. Beta-amyloid is a peptide that forms amyloid plaques in the brains of Alzheimer's disease (AD) patients.

IC50 & Target

Amyloid-β[1]
体外実験

β-Amyloid (1-15) is produced by concerted β- and α-secretase cleavage of amyloid-β protein precursor (AβPP). β-Amyloid (1-15) seems to be a sensitive acute pharmacodynamic biomarker for γ-secretase inhibition and may have several advantages compared to measuring longer CSF Aβ species. [1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

β-Amyloid (1-15) 関連抗体
分子量

1826.84

分子式

C78H107N25O27
CAS 番号
Appearance

Solid

Color

White to off-white

Sequence

Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln
Sequence Shortening

DAEFRHDSGYEVHHQ
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件
Sealed storage, away from moisture
Powder -80°C 2 years
  -20°C 1 year

*The compound is unstable in solutions, freshly prepared is recommended.
溶剤 & 溶解度
体外: 

H2O : 50 mg/mL (27.37 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.5474 mL 2.7370 mL 5.4739 mL
5 mM 0.1095 mL 0.5474 mL 1.0948 mL
10 mM 0.0547 mL 0.2737 mL 0.5474 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始）

C1

×
体積 （開始）

V1

=
濃度 （終了）

C2

×
体積 （終了）

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
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参考文献

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.5474 mL 2.7370 mL 5.4739 mL 13.6848 mL
5 mM 0.1095 mL 0.5474 mL 1.0948 mL 2.7370 mL
10 mM 0.0547 mL 0.2737 mL 0.5474 mL 1.3685 mL
15 mM 0.0365 mL 0.1825 mL 0.3649 mL 0.9123 mL
20 mM 0.0274 mL 0.1368 mL 0.2737 mL 0.6842 mL
25 mM 0.0219 mL 0.1095 mL 0.2190 mL 0.5474 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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β-Amyloid (1-15) Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

β-Amyloid (1-15)183745-81-5Amyloid β-Protein (1-15)Amyloid-ββ-amyloid peptideAβAbetaInhibitorinhibitorinhibit

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製品名:
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製品番号:
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