Acetyl tetrapeptide-3

Name: Acetyl tetrapeptide-3
Brand: MedChemExpress
SKU: HY-W129161
Rating: 4.5 (0 reviews)

Cat. No.: HY-W129161 Pureza: 98.86%: Ficha de datos
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Acetyl tetrapeptide-3 is a synthetic peptide. Acetyl tetrapeptide-3 enhances the adhesion of hair follicles to the scalp but also promotes the development of new hair follicles. Acetyl tetrapeptide-3 stimulates the synthesis of collagen III in hair follicles. Acetyl tetrapeptide-3 combined with Biochanin A (HY-14595) and ginseng extracts, can stimulate dermal papilla extracellular matrix (ECM) proteins by increasing hydroxyproline, Collagen Type 3, and laminin, yielding a significant improvement in hair follicle size and hair anchoring.

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Síntesis de péptidos personalizados

Acetyl tetrapeptide-3 Estructura química

No. CAS : 827306-88-7

Tamaño	Stock	Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water ready for reconstitution	En stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	En stock	Estimated Time of Arrival: December 31
Solid
10 mg	En stock	Estimated Time of Arrival: December 31
25 mg	En stock	Estimated Time of Arrival: December 31
50 mg	En stock	Estimated Time of Arrival: December 31
100 mg	Obtener un presupuesto
200 mg	Obtener un presupuesto

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Descripciòn

In Vitro

Acetyl tetrapeptide-3 (10-100 μM) increases the amount of collagen III synthesized by human dermal papilla cells^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

509.60

Fòrmula

C₂₂H₃₉N₉O₅

No. CAS

827306-88-7

Appearance

Solid

Color

Off-white to light yellow

Sequence

Ac-Lys-Gly-His-Lys-NH2

Sequence Shortening

Ac-KGHK-NH2

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvente y solubilidad

In Vitro:

H₂O : 116.67 mg/mL (228.94 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.9623 mL	9.8116 mL	19.6232 mL
5 mM	0.3925 mL	1.9623 mL	3.9246 mL
10 mM	0.1962 mL	0.9812 mL	1.9623 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Calculadora de molaridad
Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Pureza y Documentación

Purity: 98.86%

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Ficha de datos (272 KB) SDS (393 KB)

COA (247 KB) HNMR (297 KB) RP-HPLC (257 KB) MS (68 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. Suparuj Lueangarun, et al. An Herbal Extract Combination (Biochanin A, Acetyl tetrapeptide-3, and Ginseng Extracts) versus 3% Minoxidil Solution for the Treatment of Androgenetic Alopecia: A 24-week, Prospective, Randomized, Triple-blind, Controlled Trial. J Clin Aesthet Dermatol. 2020 Oct;13(10):32-37. [Content Brief]

[2]. Bui Thi Phuong Hai, et al., (2025). TOTAL SYNTHESIS OF THE ACTIVE INGREDIENT ACETYL TETRAPEPTIDE-3 FOR HAIR LOSS TREATMENT AND SCALP CARE. Natural sciences 70(1).

[3]. Li-Wei Tian, et al., Co-delivery of bioactive peptides by nanoliposomes for promotion of hair growth, Journal of Drug Delivery Science and Technology, Volume 72, 2022, 103381, ISSN 1773-2247.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.9623 mL	9.8116 mL	19.6232 mL	49.0581 mL
	5 mM	0.3925 mL	1.9623 mL	3.9246 mL	9.8116 mL
	10 mM	0.1962 mL	0.9812 mL	1.9623 mL	4.9058 mL
	15 mM	0.1308 mL	0.6541 mL	1.3082 mL	3.2705 mL
	20 mM	0.0981 mL	0.4906 mL	0.9812 mL	2.4529 mL
	25 mM	0.0785 mL	0.3925 mL	0.7849 mL	1.9623 mL
	30 mM	0.0654 mL	0.3271 mL	0.6541 mL	1.6353 mL
	40 mM	0.0491 mL	0.2453 mL	0.4906 mL	1.2265 mL
	50 mM	0.0392 mL	0.1962 mL	0.3925 mL	0.9812 mL
	60 mM	0.0327 mL	0.1635 mL	0.3271 mL	0.8176 mL
	80 mM	0.0245 mL	0.1226 mL	0.2453 mL	0.6132 mL
	100 mM	0.0196 mL	0.0981 mL	0.1962 mL	0.4906 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.