2. GPCR/G Protein Neuronal Signaling
  3. Melanocortin Receptor
  4. Agouti-related Protein (AGRP) (83-132) Amide (human) (TFA)

Agouti-related Protein (AGRP) (83-132) Amide (human) (TFA) 

Cat. No.: HY-P3561A Purity: 95.76%
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Agouti-related Protein (AGRP) (83-132) Amide (human) TFA is a fragment of agouti-related protein (AGRP) which is a protein found in abundance in the arcuate nucleus of the hypothalamus. AgRP primarily acts as an inverse agonist for the melanocortin-4 receptor (MC4R) to increase food intake.

For research use only. We do not sell to patients.

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Agouti-related Protein (AGRP) (83-132) Amide (human) (TFA) Chemical Structure

Agouti-related Protein (AGRP) (83-132) Amide (human) (TFA) Chemical Structure

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Based on 1 publication(s) in Google Scholar

Other Forms of Agouti-related Protein (AGRP) (83-132) Amide (human) (TFA):

Agouti-related Protein (AGRP) (83-132) Amide (human) (TFA) Related Antibodies

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Description

Agouti-related Protein (AGRP) (83-132) Amide (human) TFA is a fragment of agouti-related protein (AGRP) which is a protein found in abundance in the arcuate nucleus of the hypothalamus. AgRP primarily acts as an inverse agonist for the melanocortin-4 receptor (MC4R) to increase food intake[1][2].

IC50 & Target

Melanocortin-4 receptor[2]
In Vivo

Agouti-related Protein (AGRP) (83-132) increases food intake and decreases spontaneous locomotor activity in rats[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

5790.62 (free acid)

Formula

C235H362N76O67S11.xC2HF3O2
Appearance

Solid

Color

White to off-white

Sequence

Ser-Ser-Arg-Arg-Cys-Val-Arg-Leu-His-Glu-Ser-Cys-Leu-Gly-Gln-Gln-Val-Pro-Cys-Cys-Asp-Pro-Cys-Ala-Thr-Cys-Tyr-Cys-Arg-Phe-Phe-Asn-Ala-Phe-Cys-Tyr-Cys-Arg-Lys-Leu-Gly-Thr-Ala-Met-Asn-Pro-Cys-Ser-Arg-Thr-NH2 (Disulfide bridge: Cys1-Cys4; Cys2-Cys6; Cys3-Cys9; Cys5-Cys10; Cys7-Cys8)
Sequence Shortening

SSRRCVRLHESCLGQQVPCCDPCATCYCRFFNAFCYCRKLGTAMNPCSRT-NH2 (Disulfide bridge: Cys1-Cys4; Cys2-Cys6; Cys3-Cys9; Cys5-Cys10; Cys7-Cys8)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Purity & Documentation

Purity: 96.96%

COA (246 KB) RP-HPLC (114 KB) MS (195 KB)

Handling Instructions (2659 KB)
References
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Agouti-related Protein (AGRP) (83-132) Amide (human) (TFA) Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Agouti-related Protein (AGRP) (83-132) Amide (human) (TFA)Melanocortin ReceptorMC Receptorfood intakemelanocortin-4 receptorhypothalamusagouti-related proteinInhibitorinhibitorinhibit

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