Agouti-related Protein (AGRP) (83-132) Amide (human) TFA

製品番号: HY-P3561A 純度: 95.41%: Data Sheet SDS COA 取扱説明書
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Agouti-related Protein (AGRP) (83-132) Amide (human) TFA is a fragment of agouti-related protein (AGRP) which is a protein found in abundance in the arcuate nucleus of the hypothalamus. AgRP primarily acts as an inverse agonist for the melanocortin-4 receptor (MC4R) to increase food intake.

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Agouti-related Protein (AGRP) (83-132) Amide (human) TFA 構造式

容量	価格（税別）	在庫状況	数量
1 mg	$750	在庫あり	Estimated Time of Arrival: December 31
5 mg	$1500	在庫あり	Estimated Time of Arrival: December 31
10 mg	$2250	お問い合わせ
50 mg		お問い合わせ
100 mg		お問い合わせ

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Other Forms of Agouti-related Protein (AGRP) (83-132) Amide (human) TFA:

Agouti-related Protein (AGRP) (83-132) Amide (human) お問い合わせ

Melanocortin Receptor アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

MC1R MC3R MC2R MC4R MC5R

生物活性
純度とドキュメンテーション
参考文献
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製品説明	Agouti-related Protein (AGRP) (83-132) Amide (human) TFA is a fragment of agouti-related protein (AGRP) which is a protein found in abundance in the arcuate nucleus of the hypothalamus. AgRP primarily acts as an inverse agonist for the melanocortin-4 receptor (MC4R) to increase food intake^[1]^[2].
IC₅₀ & Target	Melanocortin-4 receptor^[2]
体内実験	Agouti-related Protein (AGRP) (83-132) increases food intake and decreases spontaneous locomotor activity in rats^[2]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	5676.57 (free base)
分子式	C₂₃₅H₃₆₂N₇₆O₆₇S₁₁.xC₂HF₃O₂
Appearance	Solid
Color	White to off-white
Sequence	Ser-Ser-Arg-Arg-Cys-Val-Arg-Leu-His-Glu-Ser-Cys-Leu-Gly-Gln-Gln-Val-Pro-Cys-Cys-Asp-Pro-Cys-Ala-Thr-Cys-Tyr-Cys-Arg-Phe-Phe-Asn-Ala-Phe-Cys-Tyr-Cys-Arg-Lys-Leu-Gly-Thr-Ala-Met-Asn-Pro-Cys-Ser-Arg-Thr-NH2 (Disulfide bridge: Cys1-Cys4; Cys2-Cys6; Cys3-Cys9; Cys5-Cys10; Cys7-Cys8)
Sequence Shortening	SSRRCVRLHESCLGQQVPCCDPCATCYCRFFNAFCYCRKLGTAMNPCSRT-NH2 (Disulfide bridge: Cys1-Cys4; Cys2-Cys6; Cys3-Cys9; Cys5-Cys10; Cys7-Cys8)
輸送条件	Room temperature in continental US; may vary elsewhere.
保管条件	polypeptide, sealed storage, away from moisture and light, under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (polypeptide, sealed storage, away from moisture and light, under nitrogen)
溶剤 & 溶解度	体外: DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) Molarity Calculator Dilution Calculator Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Mass = Concentration × Volume × Molecular Weight * Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final) 一般には略語で表示されます：C₁V₁ = C₂V₂ 濃度 _（開始） C1 × 体積 _（開始） V1 = 濃度 _（終了） C2 × 体積 _（終了） V2 In Vivo Dissolution Calculator Please enter the basic information of animal experiments: Dosage mg/kg Animal weight (per animal) g Dosing volume (per animal) μL Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments. Calculation results: Working solution concentration: mg/mL
純度とドキュメンテーション	純度: 96.96% Select Batch: データシート (308 KB) SDS (252 KB) COA (246 KB) RP-HPLC (114 KB) MS (195 KB) 取扱説明書 (2659 KB)
参考文献	[1]. Donald W. Pfaff, et al. Chapter 1 - Hormones Can Facilitate or Suppress Behaviors. Principles of Hormone/Behavior Relations (Second Edition). Academic Press, 2018, Pages 3-26, ISBN 9780128113714. [2]. Tang-Christensen M, et al. Central administration of ghrelin and agouti-related protein (83-132) increases food intake and decreases spontaneous locomotor activity in rats. Endocrinology. 2004 Oct;145(10):4645-52. [Content Brief]