2. Apoptosis
  3. Apoptosis
  4. DL-α-Tocotrienol

Alpha-Tocotrienol is a vitamin E analog with anti-apoptotic neuroprotective action and antioxidant properties. Alpha-Tocotrienol prevents oxidative stress-independent apoptotic cell death, DNA cleavage, and nuclear morphological changes.

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DL-α-Tocotrienol

DL-α-Tocotrienol Estructura química

No. CAS : 1721-51-3

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Other Forms of DL-α-Tocotrienol:

DL-α-Tocotrienol Related Antibodies

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Descripciòn

Alpha-Tocotrienol is a vitamin E analog with anti-apoptotic neuroprotective action and antioxidant properties. Alpha-Tocotrienol prevents oxidative stress-independent apoptotic cell death, DNA cleavage, and nuclear morphological changes[1].

Cellular Effect
Cell Line Type Value Description References
HepG2 IC50
110 μM
Compound: d,l-alpha-tocotrienol
Compound is evaluated for the inhibition of cholesterol synthesis in HepG2 cells for an incubation time of 6 (h)
Compound is evaluated for the inhibition of cholesterol synthesis in HepG2 cells for an incubation time of 6 (h)
[PMID: 1433170]
HepG2 IC50
380 μM
Compound: d,l-alpha-tocotrienol
Compound is evaluated for the inhibition of cholesterol synthesis in HepG2 cells for an incubation time of 2 (h)
Compound is evaluated for the inhibition of cholesterol synthesis in HepG2 cells for an incubation time of 2 (h)
[PMID: 1433170]
HepG2 IC50
94 μM
Compound: d,l-alpha-tocotrienol
Compound is evaluated for the inhibition of cholesterol synthesis in HepG2 cells for an incubation time of 4 (h)
Compound is evaluated for the inhibition of cholesterol synthesis in HepG2 cells for an incubation time of 4 (h)
[PMID: 1433170]
Peso molecular

424.66

Fòrmula

C29H44O2
No. CAS
SMILES

OC1=C(C)C(C)=C2C(CCC(CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/C)(C)O2)=C1C
Structure Classification
Initial Source

human blood
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
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DL-α-Tocotrienol Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DL-α-Tocotrienol1721-51-3Apoptosisanti-apoptoticvitamin E analogantioxidant;Inhibitorinhibitorinhibit

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Nombre del producto:
DL-α-Tocotrienol
Cat. No.:
HY-113091
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