Amino Tadalafil

製品番号: HY-117109 純度: 98.89%: Data Sheet SDS COA 取扱説明書
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Amino Tadalafil is a phosphodiesterase type 5 (PDE5) inhibitor analog and tadalafil structural analog. Amino Tadalafil can be specifically detected by anti-tadalafil polyclonal antibodies, with a cross-reactivity of 105.2% with tadalafil. Amino Tadalafil can be incorporated into dietary supplements.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

Amino Tadalafil 構造式

CAS 番号 : 385769-84-6

容量	価格（税別）	在庫状況	数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 33	在庫あり	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 33	在庫あり	Estimated Time of Arrival: December 31
Solid
5 mg	$30	在庫あり	Estimated Time of Arrival: December 31
10 mg	$45	在庫あり	Estimated Time of Arrival: December 31
25 mg	$85	在庫あり	Estimated Time of Arrival: December 31
50 mg	$125	在庫あり	Estimated Time of Arrival: December 31
100 mg	$190	在庫あり	Estimated Time of Arrival: December 31
200 mg		お問い合わせ
500 mg		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

Other Forms of Amino Tadalafil:

Amino Tadalafil (Standard) お問い合わせ

おすすめ

•関連スクリーニングライブラリ:

•関連小分子:

•関連タンパク質:

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
MRC5	IC₅₀	>64 3 Compound: 18	Cytotoxicity against human MRC5 SV2 cells after 72 hrs Cytotoxicity against human MRC5 SV2 cells after 72 hrs	[PMID: 21504142]
MRC5	IC₅₀	> 64 3 Compound: 18	Cytotoxicity against human MRC5 SV2 cells after 72 hrs Cytotoxicity against human MRC5 SV2 cells after 72 hrs	[PMID: 21504142]
MRC5	IC₅₀	> 64 3 Compound: 18	Cytotoxicity against human MRC5 SV2 cells after 72 hrs Cytotoxicity against human MRC5 SV2 cells after 72 hrs	[PMID: 21504142]

体外実験

Amino Tadalafil shows high binding affinity to the anti-tadalafil polyclonal antibody, with an IC₅₀ of 0.88 ng/mL and 102.2% cross-reactivity relative to tadalafil^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

390.39

分子式

C₂₁H₁₈N₄O₄

CAS 番号

385769-84-6

Appearance

Solid

Color

White to off-white

SMILES

O=C([C@@]1([H])CC2=C([C@@H](C3=CC=C(OCO4)C4=C3)N15)NC6=C2C=CC=C6)N(N)CC5=O

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶剤 & 溶解度

体外:

DMSO : 125 mg/mL (320.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.5615 mL	12.8077 mL	25.6154 mL
5 mM	0.5123 mL	2.5615 mL	5.1231 mL
10 mM	0.2562 mL	1.2808 mL	2.5615 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

純度とドキュメンテーション

純度: 98.89%

Select Batch:

データシート (278 KB) SDS (393 KB)

COA (258 KB) HNMR (270 KB) RP-HPLC (254 KB) MS (230 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Hadwiger ME, et al. Identification of amino-tadalafil and rimonabant in electronic cigarette products using high pressure liquid chromatography with diode array and tandem mass spectrometric detection. J Chromatogr A. 2010;1217(48):7547-7555. [Content Brief]

[2]. Fan He, et al. Development of a skeleton-specific antibody and Au nanoparticle-based immunochromatographic sensor for simultaneous detection of various tadalafil adulterants in health food. Food and Agricultural Immunology. 2019, VOL. 30, NO. 1, 349–368.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.5615 mL	12.8077 mL	25.6154 mL	64.0385 mL
	5 mM	0.5123 mL	2.5615 mL	5.1231 mL	12.8077 mL
	10 mM	0.2562 mL	1.2808 mL	2.5615 mL	6.4039 mL
	15 mM	0.1708 mL	0.8538 mL	1.7077 mL	4.2692 mL
	20 mM	0.1281 mL	0.6404 mL	1.2808 mL	3.2019 mL
	25 mM	0.1025 mL	0.5123 mL	1.0246 mL	2.5615 mL
	30 mM	0.0854 mL	0.4269 mL	0.8538 mL	2.1346 mL
	40 mM	0.0640 mL	0.3202 mL	0.6404 mL	1.6010 mL
	50 mM	0.0512 mL	0.2562 mL	0.5123 mL	1.2808 mL
	60 mM	0.0427 mL	0.2135 mL	0.4269 mL	1.0673 mL
	80 mM	0.0320 mL	0.1601 mL	0.3202 mL	0.8005 mL
	100 mM	0.0256 mL	0.1281 mL	0.2562 mL	0.6404 mL

Amino Tadalafil Related Classifications

Others

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量		濃度		体積		分子量 *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）	×	体積 _（開始）	=	濃度 _（終了）	×	体積 _（終了）
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Amino Tadalafil385769-84-6Drug DerivativeDrug derivativeAuNPs-ICS assayE-Cialis electronic cigarette cartridgestadalafilrefill liquidshealth foodHPLC-DAD-MMI-MS/MSdietary supplementsanti-tadalafil polyclonal antibodyphosphodiesterase type 5Inhibitorinhibitorinhibit

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