S100A6BP Antibody (YA4763)

Cat. No.: HY-P85071: Data Sheet User Guide for Antibodies
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S100A6BP Antibody (YA4763) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Calcyclin.

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사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

S100A6BP Antibody (YA4763) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to Calcyclin.

Host

Mouse

Clonality

Monoclonal

분자량

Predicted band size: 26 kDa;

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9HB71

Gene ID

27101 [NCBI]

Immunogen

Purified recombinant fragment of Calcyclin( aa1-228) expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:200-1000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-500
IF-Tissue IF-Tissue: Immunofluorescence-Tissue	1:50-500
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-500
IP IP: Immunoprecipitation	1-2μg per 100-500μg Total protein
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:50-3000

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified

Appearance

Liquid

Formulation

Supplied in PBS with < 0.1% sodium azide and 0.1% gelatin.

Storage & Stability

Stored at 2-8°C for 1 year, do not freeze.

선적

Shipping with blue ice.

Background

Function：May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1)

Subcellular Localization：Nucleus; Cytoplasm

Isoforms & Post-Translational Modification：Q9HB71 has 3 isomers: Q9HB71-1: 26210 Da (predicted); Q9HB71-2: 8956 Da (predicted); Q9HB71-3: 21228 Da (predicted).
Phosphorylated on serine residues. Phosphorylated upon induction by RA or at high calcium concentrations

Subunit：Homodimer. Interacts with proteins of the S100 family S100A1, S100A6, S100B, S100P and S100A12 in a calcium-dependent manner (By similarity). Component of some large E3 complex at least composed of UBE2D1, SIAH1, CACYBP/SIP, SKP1, APC and TBL1X. Interacts directly with SIAH1, SIAH2 and SKP1

Synonyms

CACYBP; S100A6BP; SIP; PNAS-107; Calcyclin-binding protein; CacyBP; hCacyBP; S100A6-binding protein; Siah-interacting protein

각종 서류

User Guide for Antibodies (1077 KB)