PI3 Kinase p55 gamma Antibody (YA4639)

Cat. No.: HY-P80866A: Fiche technique User Guide for Antibodies
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PI3 Kinase p55 gamma Antibody (YA4639) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PI3 Kinase p55 gamma.

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Size		Stock
50 μL		Obtenir un devis
100 μL		Obtenir un devis

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Description
Références

Description

PI3 Kinase p55 gamma Antibody (YA4639) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PI3 Kinase p55 gamma.

Host

Rabbit

Clonality

Monoclonal,Recombinant

Masse moléculaire

Predicted band size: 54 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q92569

Gene ID

8503 [NCBI]

Immunogen

Synthetic peptide corresponding to Human PI3 Kinase p55 gamma.The exact sequence is proprietary to MCE.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200

Pureté	affinity purified	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Livraison

Shipping with blue ice.

Background

Function：Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1

Expression：
Tissue_specificity:It is found in the highest concentrations in the brain and testes. Lower concentrations are found in adipose tissue, kidneys, heart, lungs, and skeletal muscle.

Isoforms & Post-Translational Modification：Q92569 has 3 isomers: Q92569-1: 54448 Da (predicted); Q92569-2: 47348 Da (predicted); Q92569-3: 43465 Da (predicted).

Subunit：Heterodimer of a regulatory subunit PIK3R3 and a p110 catalytic subunit (PIK3CA, PIK3CB or PIK3CD). Interacts with AXL

Database

Entrez Gene: 8503 Human ; 18710 Mouse ; 60664 Rat

SwissProt: Q92569 Human ; Q64143 Mouse ; Q63789 Rat

OMIM: 606076 Human

Research Field

Signal Transduction

Synonyms

GRB1; P85A; PI3-kinase p85-alpha subunit; PI3K; PI3K p85-alpha; P55G; PI3-kinase p85-gamma subunit; PI3K p85-gamma

Documentation

User Guide for Antibodies (1077 KB)

Références

[1]. /biology-dictionary/hepg2-cell.html [Content Brief]