PTPRD Antibody (YA3893)

Cat. No.: HY-P84196: Data Sheet User Guide for Antibodies
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PTPRD Antibody (YA3893) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PTPRD.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL	Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation
References

Description

PTPRD Antibody (YA3893) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PTPRD.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 214.8 kDa;

Observed band size: 175 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

P23468

Gene ID

5789 [NCBI]

Immunogen

Purified recombinant fragment of human PTPRD (AA: extra 1077-1265) expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
FC FC: Flow Cytometry	1:200-1:400
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS with 0.05% sodium azide

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Can bidirectionally induce pre- and post-synaptic differentiation of neurons by mediating interaction with IL1RAP and IL1RAPL1 trans-synaptically. Involved in pre-synaptic differentiation through interaction with SLITRK2

Subcellular Localization：Membrane; Single-pass type I membrane protein

Isoforms & Post-Translational Modification：P23468 has 7 isomers: P23468-1: 214760 Da (predicted); P23468-2: 212133 Da (predicted); P23468-3: 156088 Da (predicted); P23468-4: 169474 Da (predicted); P23468-5: 169606 Da (predicted); P23468-6: 169693 Da (predicted); P23468-7: 169277 Da (predicted).
A cleavage occurs, separating the extracellular domain from the transmembrane segment. This process called 'ectodomain shedding' is thought to be involved in receptor desensitization, signal transduction and/or membrane localization

Subunit：Interacts with PPFIA1, PPFIA2 and PPFIA3 (PubMed:9624153). Interacts (via extracellular domain) with SLITRK4 (via LRR 1 and 2 repeats). Interacts with SLITRK2; induces presynaptic differentiation. Interacts (via the second immunoglobilin domain) with IL1RAPL1 (via the first immunoglobilin domain); induces pre- and postsynaptic differentiation of neurons and synapse formation. Interacts (via the third immunoglobilin domain) with IL1RAP (via the first immunoglobilin domain); induces pre- and postsynaptic differentiation of neurons (By similarity)

Synonyms

HPTP; PTPD; HPTPD; HPTPDELTA; RPTPDELTA

Documentation

User Guide for Antibodies (1077 KB)

References

[1]. /biology-dictionary/smmc-7721-cell.html [Content Brief]