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atx-001

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Inhibitors & Agonists

1

Inhibitory Antibodies

Cat. No. Nombre del producto Target Áreas de investigación Chemical Structure
  • HY-P991049
    Atrosimab

    ATM-001

    		 TNF Receptor Metabolic Disease Inflammation/Immunology
    Atrosimab is an Fv-Fc1K fusion protein with an EC50 value of 0.37 nM against humans. Atrosimab inhibits TNF-induced TNFR1 activation, release of IL-6 and IL-8, and cell death, and alleviates neuroinflammation. Atrosimab is applicable to research related to inflammatory diseases, neurodegenerative diseases, acute and chronic inflammation, experimental arthritis, non-alcoholic steatohepatitis, and experimental autoimmune encephalomyelitis .
    Atrosimab
  • HY-18967
    Caficrestat

    AT-001; Aldose reductase-IN-1

    		 Aldose Reductase Metabolic Disease
    Caficrestat (AT-001) is an orally active aldose reductase inhibitor. Caficrestat can be used in the study of diabetic cardiomyopathy .
    Caficrestat

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