(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (Synonyms: Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate)

Cat. No.: HY-D0177 Purity: 98.0%: Data Sheet
COA

SDS
Handling Instructions
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(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate) is a peptide coupling reagent and BOP analog. (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate promotes the reaction of amino and carboxyl groups to form peptide bonds. (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate can be used in the synthesis of peptide compounds.

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(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate 화학구조

CAS No. : 128625-52-5

사이즈	재고	수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	해외재고보유	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	해외재고보유	Estimated Time of Arrival: December 31
Solid
25 g	해외재고보유	Estimated Time of Arrival: December 31
50 g	해외재고보유	Estimated Time of Arrival: December 31
100 g	해외재고보유	Estimated Time of Arrival: December 31
250 g	해외재고보유	Estimated Time of Arrival: December 31
500 g	해외재고보유	Estimated Time of Arrival: December 31
> 100 g	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

In Vitro

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate is used for the reaction of vanillin acid with various amine compounds to form amide bonds^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

520.39

화학식

C₁₈H₂₈F₆N₆OP₂

CAS No.

128625-52-5

Appearance

Solid

Color

White to off-white

SMILES

F[P-](F)(F)(F)(F)F.C12=CC=CC=C1N=NN2O[P+](N3CCCC3)(N4CCCC4)N5CCCC5

선적

Room temperature in continental US; may vary elsewhere.

보관

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

용액&용해도

In Vitro:

DMSO : 200 mg/mL (384.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.9216 mL	9.6082 mL	19.2164 mL
5 mM	0.3843 mL	1.9216 mL	3.8433 mL
10 mM	0.1922 mL	0.9608 mL	1.9216 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 99.90%

Select Batch:

Data Sheet (273 KB) SDS (597 KB)

COA (252 KB) HNMR (131 KB)

Handling Instructions (2659 KB)

References

[1]. Coste J, et al., PyBOP®: A new peptide coupling reagent devoid of toxic by-product[J]. Tetrahedron Letters, 1990, 31(2): 205-208.

[2]. Frérot E, et al. PyBOP® and PyBroP: Two reagents for the difficult coupling of the α, α-dialkyl amino acid, Aib. Tetrahedron, 1991, 47(2): 259-270.

[3]. Santos Oliveira AJM, et al. Amides Derived from Vanillic Acid: Coupling Reactions, Antimicrobial Evaluation, and Molecular Docking. Biomed Res Int. 2019 Apr 15;2019:9209676. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.9216 mL	9.6082 mL	19.2164 mL	48.0409 mL
	5 mM	0.3843 mL	1.9216 mL	3.8433 mL	9.6082 mL
	10 mM	0.1922 mL	0.9608 mL	1.9216 mL	4.8041 mL
	15 mM	0.1281 mL	0.6405 mL	1.2811 mL	3.2027 mL
	20 mM	0.0961 mL	0.4804 mL	0.9608 mL	2.4020 mL
	25 mM	0.0769 mL	0.3843 mL	0.7687 mL	1.9216 mL
	30 mM	0.0641 mL	0.3203 mL	0.6405 mL	1.6014 mL
	40 mM	0.0480 mL	0.2402 mL	0.4804 mL	1.2010 mL
	50 mM	0.0384 mL	0.1922 mL	0.3843 mL	0.9608 mL
	60 mM	0.0320 mL	0.1601 mL	0.3203 mL	0.8007 mL
	80 mM	0.0240 mL	0.1201 mL	0.2402 mL	0.6005 mL
	100 mM	0.0192 mL	0.0961 mL	0.1922 mL	0.4804 mL

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate Related Classifications

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium128625-52-5Benzotriazole-1-yl-oxytripyrrolidinophosphoniumBiochemical Assay Reagentspeptide coupling reagentsolid phase synthesis testInhibitorinhibitorinhibit

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(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate (Synonyms: Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate)

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate Related Antibodies

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Biological Activity

순도&문서

References

고객리뷰

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate Related Antibodies

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