Boc-NH-PEG6-CH2COOH

Name: Boc-NH-PEG6-CH2COOH
Brand: MedChemExpress
SKU: HY-140477
Rating: 4.5 (0 reviews)

Cat. No.: HY-140477 Pureté: 98.0%: Fiche technique
COA

SDS
Instruction de manipulation
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Boc-NH-PEG6-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

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Boc-NH-PEG6-CH2COOH Chemical Structure

CAS No. : 391684-36-9

Size	Stock	Quantité
100 mg	En stock	Estimated Time of Arrival: December 31
250 mg	En stock	Estimated Time of Arrival: December 31
1 g	En stock	Estimated Time of Arrival: December 31
5 g	En stock	Estimated Time of Arrival: December 31
10 g	Obtenir un devis
50 g	Obtenir un devis

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•Related Small Molecules:

•Related Proteins:

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PEG Linkers Alkyl-Chain Linkers Alkyl/ether Linkers

Activité biologique
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Description

Boc-NH-PEG6-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target

PEGs

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Masse moléculaire

439.50

Formule

C₁₉H₃₇NO₁₀

CAS No.

391684-36-9

Appearance

Viscous Liquid

Color

Colorless to light yellow

SMILES

O=C(OC(C)(C)C)NCCOCCOCCOCCOCCOCCOCC(O)=O

Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Pureté et documentation

Purity: ≥98.0%

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Fiche technique (262 KB) SDS (394 KB)

COA (240 KB) HNMR (131 KB) LCMS (268 KB)

Instruction de manipulation (2659 KB)

Références

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 [Content Brief]