Bovine Serum Albumin (Low Endotoxin,Fatty acid free)  (Synonyms: Albumin bovine serum (Low Endotoxin,Fatty acid free); BSA (Low Endotoxin,Fatty acid free))

Bovine Serum Albumin (Low Endotoxin,Fatty acid free) (BSA) is a 583 amino acid globular protein and oligonucleotide binding protein composed of three homologous full α domains. Bovine Serum Albumin (Low Endotoxin,Fatty acid free) (BSA) blocks the overall binding of oligonucleotides to cells. Bovine Serum Albumin (Low Endotoxin,Fatty acid free) (BSA) regulates the development of hamster embryos and induces arthritis^[1][2][3][4].

Bovine Serum Albumin (Low Endotoxin,Fatty acid free) (1%, add to culture medium; 2 h) serves to block overall association of oligonucleotide with HL60 cells, and it is the main cell surface protein binding oligonucleotides^[2].
Bovine Serum Albumin (Low Endotoxin,Fatty acid free) (3 mg/mL) shows variable effects on the development of hamster 2-cell embryos in vitro, with some lots (BSA-2 and BSA-3) stimulating development and some lots (BSA-1 and BSA-4) inhibiting development^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Bovine Serum Albumin (Low Endotoxin,Fatty acid free) (immunization: 1.5 mL of 5 mg/mL BSA; challenge: 0.5 mL of 30% BSA; immunization on day -17, challenge on day 0) induces arthritis in rabbits^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

9048-46-8

Solid

Light yellow to khaki

[Bovine Serum Albumin (Low Endotoxin,Fatty acid free)]

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Holm NK, et al. Aggregation and fibrillation of bovine serum albumin. Biochim Biophys Acta. 2007 Sep;1774(9):1128-38.  [Content Brief]

  [2]. Geselowitz DA, et al. Bovine serum albumin is a major oligonucleotide-binding protein found on the surface of cultured cells. Antisense Res Dev. 1995 Fall;5(3):213-7.  [Content Brief]

  [3]. McKiernan SH, et al. Different lots of bovine serum albumin inhibit or stimulate in vitro development of hamster embryos. In Vitro Cell Dev Biol. 1992 Mar;28A(3 Pt 1):154-6.  [Content Brief]

  [4]. Sharma ML, et al. Anti-arthritic activity of boswellic acids in bovine serum albumin (BSA)-induced arthritis. Int J Immunopharmacol. 1989;11(6):647-52.  [Content Brief]