CBG-549-QSY7 

CBG-549-QSY7 is a Dylight 549-labeled SNAP tag fluorescent probe (Ex/Em: 546 nm/580 nm), specially designed for non-washable fluorescence imaging applications. CBG-549-QSY7 employs an intramolecular FRET quenching mechanism: intramolecular fluorescence quenching occurs before binding to the SNAP tag, and upon binding, the quenching group is cleaved, releasing fluorescence. The background fluorescence of CBG-549-QSY7 is extremely low, and clear cell membrane images can be obtained after 5 minutes of incubation^[1].

1971.64

C₉₃H₁₀₃ClN₁₃Na₃O₁₉S₅

CC[N+]1=C(C(CCCS(=O)(O[Na])=O)(C2=C1C=CC(S(=O)([O-])=O)=C2)C)/C=C/C=C3N(C4=CC=C(C=C4C/3(CCCC(NCC5=CC=C(C=C5)COC6=NC(N)=NC7=C6N=C(N7)CCC(NCCCCCNC(C8CCN(CC8)S(=O)(C9=C(C=CC=C9)C%10=C%11C=CC(C=C%11OC(C%10C=C/%12)=CC%12=[N+](C%13=CC=CC=C%13)\C)N(C%14=CC=CC=C%14)C)=O)=O)=O)=O)C)S(=O)(O[Na])=O)CCCS(=O)(O[Na])=O.[Cl-]

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Sun X, et al. Development of SNAP-tag fluorogenic probes for wash-free fluorescence imaging. Chembiochem. 2011 Sep 19;12(14):2217-26.  [Content Brief]