Copper tripeptide acetate  (Synonyms: GHK-Cu acetate)

Copper tripeptide (GHK-Cu) acetate is a tripeptide. During wound healing, Copper tripeptide acetate may be freed from existing extracellular proteins via proteolysis and serves as a chemoattractant for inflammatory and endothelial cells. Copper tripeptide acetate has been shown to increase messenger RNA production for collagen, elastin, proteoglycans, and glycosaminoglycans in fibroblasts. Copper tripeptide acetate is a natural modulator of multiple cllular pathways in skin regeneration^[1].

Copper tripeptide (1 nM; 0-96 hours) acetate affects irradiated fibroblasts such that their population-doubling times approximated that of controls^[1].
Copper tripeptide (1 nM; 0-120 hours) acetate significantly produces more basic fibroblast growth factors than normal controls at a 24-hour interval of irradiated fibroblasts^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

461.96

C₁₆H₂₆CuN₆O₆

300801-03-0

CC(O)=O.NCCCC[C@@H](C([O-])=O)NC([C@H]1[N-]2[Cu+2]([NH2]CC2=O)[N]3=CNC=C3C1)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Pollard JD, et al. Effects of copper tripeptide on the growth and expression of growth factors by normal and irradiated fibroblasts. Arch Facial Plast Surg. 2005 Jan-Feb;7(1):27-31.  [Content Brief]