2. Membrane Transporter/Ion Channel
  3. CRM1
  4. CRM1 degrader 1

CRM1 degrader 1 (1l) is a low toxic chromosome region maintenance 1 (CRM1) degrader. CRM1 is the sole nuclear exporter of several tumor suppressor, a growth regulatory protein as an attractive cancer agent target. CRM1 degrader 1 induces the apoptosis in gastric carcinoma and selectively inhibits proliferation of gastric cancer.

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CRM1 degrader 1

CRM1 degrader 1 화학구조

CAS No. : 2986647-41-8

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CRM1 degrader 1 Related Antibodies

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제품 설명

CRM1 degrader 1 (1l) is a low toxic chromosome region maintenance 1 (CRM1) degrader. CRM1 is the sole nuclear exporter of several tumor suppressor, a growth regulatory protein as an attractive cancer agent target. CRM1 degrader 1 induces the apoptosis in gastric carcinoma and selectively inhibits proliferation of gastric cancer[1].

Cellular Effect
Cell Line Type Value Description References
MGC-803 IC50
2.314 μM
Compound: 1l
Antiproliferative activity against human MGC-803 cells by MTT assay
Antiproliferative activity against human MGC-803 cells by MTT assay
[PMID: 32810752]
분자량

260.33

화학식

C16H20O3
CAS No.
SMILES

CC1=CC(OC[C@H]2CC=CC(O2)=O)=C(C=C1)C(C)C
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
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CRM1 degrader 1 Related Classifications

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Keywords:

CRM1 degrader 12986647-41-8CRM1Chromosomal Maintenance 1Exportin 1XPO1low toxictumor suppressorapoptosisgastric carcinomaproliferationInhibitorinhibitorinhibit

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상품명:
CRM1 degrader 1
Cat. No.:
HY-146384
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