2986647-41-8
Chemical Structure
CRM1 degrader 1
- CAS No.: 2986647-41-8
- Formula:C16H20O3
- Molecular Weight:260.33
IUPAC Name: (R)-6-((2-isopropyl-5-methylphenoxy)methyl)-5,6-dihydro-2H-pyran-2-one
InChIKey: CHFFVRWPHNFFIX-CYBMUJFWSA-N
SMILES: CC1=CC(OC[C@H]2CC=CC(O2)=O)=C(C=C1)C(C)C
Biological Activity: CRM1 degrader 1 (1l) is a low toxic chromosome region maintenance 1 (CRM1) degrader. CRM1 is the sole nuclear exporter of several tumor suppressor, a growth regulatory protein as an attractive cancer agent target. CRM1 degrader 1 induces the apoptosis in gastric carcinoma and selectively inhibits proliferation of gastric cancer[1].
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CRM1 degrader 1 | CRM1 degrader 1 (1l) is a low toxic chromosome region maintenance 1 (CRM1) degrader. CRM1 is the sole nuclear exporter of several tumor suppressor, a growth regulatory protein as an attractive cancer agent target. CRM1 degrader 1 induces the apoptosis in gastric carcinoma and selectively inhibits proliferation of gastric cancer. | |||||||||||||||||||||
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Keywords
