CRM1 degrader 1
CRM1 degrader 1 (1l) is a low toxic chromosome region maintenance 1 (CRM1) degrader. CRM1 is the sole nuclear exporter of several tumor suppressor, a growth regulatory protein as an attractive cancer agent target. CRM1 degrader 1 induces the apoptosis in gastric carcinoma and selectively inhibits proliferation of gastric cancer.
For research use only. We do not sell to patients.
- CAS No.: 2986647-41-8
- Formula: C16H20O3
- Molecular Weight:260.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| MGC-803 | IC50 |
2.314 μM
Compound: 1l
|
Antiproliferative activity against human MGC-803 cells by MTT assay
Antiproliferative activity against human MGC-803 cells by MTT assay
|
[PMID: 32810752] |
Chemical Information
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CAS No. 2986647-41-8
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Molecular Weight 260.33
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Formula C16H20O3
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SMILES
CC1=CC(OC[C@H]2CC=CC(O2)=O)=C(C=C1)C(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)