1. GPCR/G Protein Neuronal Signaling
  2. Neurokinin Receptor
  3. (D-Pro2,D-Trp6,8,Nle10)-Neurokinin B

(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B is a competitive antagonist of Neurokinin B (Neurokinin Receptor) with a pA2 of 5.5. (D-Pro2,D-Trp6,8,Nle10)-Neurokinin B shows no influence on Substance P or Neurokinin A.

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(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B

(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B Chemische Struktur

CAS. Nr. : 109212-72-8

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Beschreibung

(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B is a competitive antagonist of Neurokinin B (Neurokinin Receptor) with a pA2 of 5.5. (D-Pro2,D-Trp6,8,Nle10)-Neurokinin B shows no influence on Substance P or Neurokinin A[1].

In Vivo

(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B (1 mg/kg i.v.) significantly reduces Substance P- and Neurokinin B- but not acetylcholine- or Neurokinin A-induced salivation. (D-Pro2,D-Trp6,8,Nle10)-Neurokinin B lowers blood pressure in anesthetized rats by 35 to 40%[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molekulargewicht

1326.50

Formel

C67H87N15O14

CAS. Nr.
Sequence Shortening

D-{D-Pro}-HDF-{D-Trp}-V-{D-Trp}-L-{Nle}-NH2

Versand

Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B
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