109212-72-8
Chemical Structure
(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B
- CAS No.: 109212-72-8
- Formula:C67H87N15O14
- Molecular Weight:1326.50
InChIKey: SBSGAKKSUHYFOA-KDICMADCSA-N
SMILES: O=C([C@@H]1N(CCC1)C([C@@H](N)CC(O)=O)=O)N[C@@H](CC2=CN=CN2)C(N[C@@H](CC(O)=O)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](C(N[C@@H](C(C)C)C(N[C@@H](C(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCCC)=O)=O)CC4=CNC5=CC=CC=C45)=O)=O)CC6=CNC7=CC=CC=C67)=O)=O)=O
Biological Activity: (D-Pro2,D-Trp6,8,Nle10)-Neurokinin B is a competitive antagonist of Neurokinin B (Neurokinin Receptor) with a pA2 of 5.5. (D-Pro2,D-Trp6,8,Nle10)-Neurokinin B shows no influence on Substance P or Neurokinin A[1].
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(D-Pro2,D-Trp6,8,Nle10)-Neurokinin B | (D-Pro2,D-Trp6,8,Nle10)-Neurokinin B is a competitive antagonist of Neurokinin B (Neurokinin Receptor) with a pA2 of 5.5. (D-Pro2,D-Trp6,8,Nle10)-Neurokinin B shows no influence on Substance P or Neurokinin A. | |||||||||||||||||||||
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Keywords