DDR1/2 inhibitor-2

製品番号: HY-156552 純度: 99.73%: Data Sheet SDS COA 取扱説明書
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Technical Support

DDR1/2 inhibitor-2 (Example 31) is a DDR1/DDR2 inhibitor, with IC₅₀ values less than 100 nM. DDR1/2 inhibitor-2 can be used for research of cancer and fibrotic diseases.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

DDR1/2 inhibitor-2 構造式

CAS 番号 : 2908756-11-4

容量	価格（税別）	在庫状況	数量
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 704	在庫あり	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 704	在庫あり	Estimated Time of Arrival: December 31
Solid
1 mg	$380	在庫あり	Estimated Time of Arrival: December 31
5 mg	$650	在庫あり	Estimated Time of Arrival: December 31
10 mg	$980	在庫あり	Estimated Time of Arrival: December 31
25 mg	$1750	在庫あり	Estimated Time of Arrival: December 31
50 mg	$2650	在庫あり	Estimated Time of Arrival: December 31
100 mg	$3950	在庫あり	Estimated Time of Arrival: December 31
200 mg		お問い合わせ
500 mg		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 0 publication(s) in Google Scholar

Discoidin Domain Receptor アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

DDR1 DDR2

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

DDR1/2 inhibitor-2 (Example 31) is a DDR1/DDR2 inhibitor, with IC₅₀ values less than 100 nM. DDR1/2 inhibitor-2 can be used for research of cancer and fibrotic diseases^[1].

IC₅₀ & Target

DDR1

DDR2

分子量

492.45

分子式

C₂₅H₁₉F₃N₆O₂

CAS 番号

2908756-11-4

Appearance

Solid

Color

White to off-white

SMILES

O=C(CN1C=CC2=C(C1=O)C(NC3=CC(C=NN4C)=C4C=C3)=CC=C2)NC5=CN=CC(C(F)(F)F)=C5

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶剤 & 溶解度

体外:

DMSO : 16.67 mg/mL (33.85 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.0307 mL	10.1533 mL	20.3066 mL
5 mM	0.4061 mL	2.0307 mL	4.0613 mL
10 mM	0.2031 mL	1.0153 mL	2.0307 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

純度とドキュメンテーション

純度: 99.73%

Select Batch:

データシート (269 KB) SDS (251 KB)

COA (247 KB) HNMR (144 KB) LCMS (95 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Inder Bhamra, et al. Phenyl- and pyridopyrazole derivatives as inhibitors of ddr1. Patent. WO2023021278.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.0307 mL	10.1533 mL	20.3066 mL	50.7666 mL
	5 mM	0.4061 mL	2.0307 mL	4.0613 mL	10.1533 mL
	10 mM	0.2031 mL	1.0153 mL	2.0307 mL	5.0767 mL
	15 mM	0.1354 mL	0.6769 mL	1.3538 mL	3.3844 mL
	20 mM	0.1015 mL	0.5077 mL	1.0153 mL	2.5383 mL
	25 mM	0.0812 mL	0.4061 mL	0.8123 mL	2.0307 mL
	30 mM	0.0677 mL	0.3384 mL	0.6769 mL	1.6922 mL