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Dehydrothio-p-toluidine  (Synonyms: DHPT)

Art. -Nr.: HY-W040269 Reinheit: 99.91%
COA
SDS
Handling Instructions Technical Support

Dehydrothio-p-toluidine (DHPT) is a chemical intermediate used in dyestuff production. Dehydrothio-p-toluidine shows inhalation toxicity in acute and subchronic conditions.

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Dehydrothio-p-toluidine

Dehydrothio-p-toluidine Chemische Struktur

CAS. Nr. : 92-36-4

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Based on 1 publication(s) in Google Scholar

Dehydrothio-p-toluidine Related Antibodies

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1 Publications Citing Use of MCE Dehydrothio-p-toluidine

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Beschreibung

Dehydrothio-p-toluidine (DHPT) is a chemical intermediate used in dyestuff production. Dehydrothio-p-toluidine shows inhalation toxicity in acute and subchronic conditions[1].

In Vivo

Dehydrothio-p-toluidine (4 h) induces salivation, pawing and chewing motions, lachrymation, sporadic fasciculations, rapid respiration and slight weight loss of mice under an average of 0.64 mg DHPT/L condition[1].
Dehydrothio-p-toluidine (4 h) induces sporadic nasal discharge and lethargy of mice under an average of 2.41 mg DHPT/L condition[1].
Dehydrothio-p-toluidine (6 h/day on 5 days followed by two rest days and then by five additional days of exposures; 0.6 mg DHPT/L) decreases the erythrocyte count, haemoglobin level and relative number of lymphocytes than in the controls, excrets a larger volume of less-concentrated urine, produces liver changes characterized by hepatocyte hyper trophy and proliferation of bile-duct epithelial cells and induxes thymic necrosis and depletion of lymphocytes after the tenth exposure[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Klinische Studie
Molekulargewicht

240.32

Formel

C14H12N2S
CAS. Nr.
Appearance

Solid

Color

Light yellow to green yellow

SMILES

CC1=CC=C2N=C(SC2=C1)C3=CC=C(C=C3)N
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Lösungsmittel & Löslichkeit
In Vitro: 

DMSO : 100 mg/mL (416.11 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.1611 mL 20.8056 mL 41.6112 mL
5 mM 0.8322 mL 4.1611 mL 8.3222 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molaritätsrechner

  • Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Reinheit & Dokumentation

Purity: 99.91%

SDS (394 KB)

COA (244 KB) HNMR (130 KB) RP-HPLC (233 KB)

Handling Instructions (2659 KB)
Verweise

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.1611 mL 20.8056 mL 41.6112 mL 104.0280 mL
5 mM 0.8322 mL 4.1611 mL 8.3222 mL 20.8056 mL
10 mM 0.4161 mL 2.0806 mL 4.1611 mL 10.4028 mL
15 mM 0.2774 mL 1.3870 mL 2.7741 mL 6.9352 mL
20 mM 0.2081 mL 1.0403 mL 2.0806 mL 5.2014 mL
25 mM 0.1664 mL 0.8322 mL 1.6644 mL 4.1611 mL
30 mM 0.1387 mL 0.6935 mL 1.3870 mL 3.4676 mL
40 mM 0.1040 mL 0.5201 mL 1.0403 mL 2.6007 mL
50 mM 0.0832 mL 0.4161 mL 0.8322 mL 2.0806 mL
60 mM 0.0694 mL 0.3468 mL 0.6935 mL 1.7338 mL
80 mM 0.0520 mL 0.2601 mL 0.5201 mL 1.3003 mL
100 mM 0.0416 mL 0.2081 mL 0.4161 mL 1.0403 mL
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Dehydrothio-p-toluidine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dehydrothio-p-toluidine92-36-4DHPTFluorescent Dyechemical intermediatebenzothiazoleinhalation toxicityacutesubchronicmiceInhibitorinhibitorinhibit

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