Didymin

Cat. No.: HY-N2068 Purity: 99.90%: FAQs
Data Sheet SDS COA Handling Instructions

Didymin, a dietary flavonoid glycoside from citrus fruits, possesses antioxidant properties. Didymin induces apoptosis by inhibiting N-Myc and upregulating RKIP in neuroblastoma.

For research use only. We do not sell to patients.

Didymin Chemical Structure

CAS No. : 14259-47-3

Size	Price	Stock	Quantity
Solution
10 mM * 1 mL in DMSO	USD 105	In-stock	Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL ready for reconstitution	USD 105	In-stock	Estimated Time of Arrival: December 31
Solid
5 mg	USD 80	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 140	In-stock	Estimated Time of Arrival: December 31
20 mg	USD 230	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

1 Publications Citing Use of MCE Didymin

•Yonsei Med J. 2022 Oct;63(10):956-965.

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Description

Didymin, a dietary flavonoid glycoside from citrus fruits, possesses antioxidant properties. Didymin induces apoptosis by inhibiting N-Myc and upregulating RKIP in neuroblastoma^[1]^[2].

Molecular Weight

594.56

Appearance

Solid

Formula

C₂₈H₃₄O₁₄

CAS No.

14259-47-3

SMILES

O=C1C[[email protected]@H](C2=CC=C(OC)C=C2)OC3=CC(O[[email protected]]4[[email protected]@H]([[email protected]]([[email protected]@H]([[email protected]@H](CO[[email protected]]5[[email protected]@H]([[email protected]@H]([[email protected]]([[email protected]](C)O5)O)O)O)O4)O)O)O)=CC(O)=C13

Structure Classification

Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 250 mg/mL (420.48 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.6819 mL	8.4096 mL	16.8192 mL
5 mM	0.3364 mL	1.6819 mL	3.3638 mL
10 mM	0.1682 mL	0.8410 mL	1.6819 mL

*Please refer to the solubility information to select the appropriate solvent.

In Vivo:

1.

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% saline
Solubility: ≥ 2.17 mg/mL (3.65 mM); Clear solution
2.

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in saline)
Solubility: ≥ 2.17 mg/mL (3.65 mM); Clear solution
3.

Add each solvent one by one: 10% DMSO 90% corn oil
Solubility: ≥ 2.17 mg/mL (3.65 mM); Clear solution

*All of the co-solvents are available by MCE.

Purity & Documentation

Purity: 99.90%

Select Batch:

Data Sheet (277 KB) SDS (393 KB)

COA (248 KB) HNMR (219 KB) LCMS (133 KB)

Handling Instructions (2659 KB)

References

[1]. Hung JY, et al. Didymin, a dietary flavonoid glycoside from citrus fruits, induces Fas-mediated apoptotic pathway in human non-small-cell lung cancer cells in vitro and in vivo. Lung Cancer. 2010 Jun;68(3):366-74. [Content Brief]

[2]. Singhal J, et al. Didymin induces apoptosis by inhibiting N-Myc and upregulating RKIP in neuroblastoma. Cancer Prev Res (Phila). 2012 Mar;5(3):473-83. [Content Brief]

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Keywords:

Didymin14259-47-3ApoptosisInhibitorinhibitorinhibit

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Didymin

Customer Review

1 Publications Citing Use of MCE Didymin

Featured Recommendations

•Related Screening Libraries:

Biological Activity

Purity & Documentation

References

Customer Review

Molarity Calculator

Dilution Calculator

The molarity calculator equation

The dilution calculator equation

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