2. Metabolic Enzyme/Protease
  3. Liposome
  4. DSPE-PEG(2000)-Amine

DSPE-PEG(2000)-Amine 

Cat. No.: HY-125924 Purity: ≥98.0%
COA Handling Instructions

DSPE-PEG(2000)-Amine, an amine derivative of phospholipid poly ethylene glycol, is used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents.

For research use only. We do not sell to patients.

DSPE-PEG(2000)-Amine Chemical Structure

DSPE-PEG(2000)-Amine Chemical Structure

CAS No. : 474922-26-4

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10 mg USD 100 In-stock
Estimated Time of Arrival: December 31
50 mg USD 220 In-stock
Estimated Time of Arrival: December 31
100 mg USD 365 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

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  • Biological Activity

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Description

DSPE-PEG(2000)-Amine, an amine derivative of phospholipid poly ethylene glycol, is used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents[1][2][3].

In Vitro

DSPE-PEG(2000)-Amine is coated on the surface of the fluorescein diacetate (FDA) nanocrystals to provide a interface for the antibody coupling. The FDA[DSPE-PEG(2000)Amine]-modified biolabels have a highly stable colloidal suspension with minimized nonspecific interactions. The adsorbed DSPE-PEG(2000)Amine layer causes the FDA nanocrystals to disperse in water and prevents their aggregation, hence conferring colloidal stability[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Appearance

Solid

Formula

(C2H4O)nC44H87N2O10P.NH3
CAS No.
SMILES

CCCCCCCCCCCCCCCCCC(OC[[email protected]]([H])(COP(OCCNC(OCCN)=O)(O)=O)OC(CCCCCCCCCCCCCCCCC)=O)=O.[n].N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro: 

Ethanol : 16.67 mg/mL (Need ultrasonic)

DMSO : 7.14 mg/mL (ultrasonic and warming and heat to 60°C)

In Vivo:
  • 1.

    Add each solvent one by one:  10% EtOH    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 1.67 mg/mL (Infinity mM); Clear solution

  • 2.

    Add each solvent one by one:  10% EtOH    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 1.67 mg/mL (Infinity mM); Clear solution

  • 3.

    Add each solvent one by one:  10% EtOH    90% corn oil

    Solubility: ≥ 1.67 mg/mL (Infinity mM); Clear solution

  • 4.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 0.71 mg/mL (Infinity mM); Clear solution

  • 5.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 0.71 mg/mL (Infinity mM); Clear solution

  • 6.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 0.71 mg/mL (Infinity mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: ≥98.0%

COA (242 KB) HNMR (247 KB) MS (83 KB)

Handling Instructions (2659 KB)
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

DSPE-PEG(2000)-Amine474922-26-4LiposomesolidlipidthermosensitiveliposomalnanoparticlesdeliveryanticanceragentsInhibitorinhibitorinhibit

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