DSPE-PEG2000-amine sodium
Based on 1 Customer Validation
DSPE-PEG2000-amine sodium is a pegylated derivative of 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (HY-112530), which can be used to synthesize solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents.
For research use only. We do not sell to patients.
- Purity: 99.98%
- CAS No.: 1292302-96-5
- Formula: (C2H4O)nC44H87N2O10P.Na
- Molecular Weight:2000 (Average)
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
DSPE-PEG2000-amine sodium prolongs the retention time of particles by coating their surface with polyethylene glycol (PEG), and ultimately prevents the particles from being opsonized, thereby blocking their subsequent clearance from the circulatory system[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1292302-96-5
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Appearance Solid
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Molecular Weight 2000 (Average)
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Formula (C2H4O)nC44H87N2O10P.Na
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Color White to off-white
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SMILES
O=P(OC[C@H](OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)(O[Na])OCCNC(OCCOCCN)=O.[n]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Purity & Documentation
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Data Sheet (264 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Gao J, et al. Affibody-based nanoprobes for HER2-expressing cell and tumor imaging. Biomaterials. 2011;32(8):2141-2148. [Content Brief]
[2]. Farinha D, et al. Combination of Gene Therapy and Chemotherapy in a New Targeted Hybrid Nanosystem to Hepatocellular Carcinoma. Int J Nanomedicine. 2024;19:12505-12527. Published 2024 Nov 22. [Content Brief]
[3]. Nandi D, et al. Nanoreporter for Real-Time Monitoring of Inflammasome Activity and Targeted Therapy. Adv Sci (Weinh). 2023;10(6):e2204900. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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