Lipid Amine

DSPE-PEG-Amine, MW 2000 (ammonium), an amine derivative of phospholipid poly ethylene glycol, is used in the synthesis of solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents.

DSPE-PEG1000-Amine (DSPE-PEG1000-NH2) ammonium is a 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol conjugate with a terminal amino group. DSPE-PEG1000-Amine ammonium can functionalize the surface of PLGA-lecithin-PEG core-shell nanoparticles to introduce positive surface charges. The amino group of DSPE-PEG1000-Amine ammonium can be converted into an aromatic aldehyde to react with the acetone-protected aromatic hydrazide on the surface of bovine carbonic anhydrase (BCA) molecules.

DSPE-PEG5000-Amine is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. DSPE-PEG5000-Amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems.

DSPE-PEG2000-amine sodium is a pegylated derivative of 1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (HY-112530), which can be used to synthesize solid lipid and thermosensitive liposomal nanoparticles for the delivery of anticancer agents.

Amino-Gly-Gly-DSPE (hydrochloride) is a specially modified phospholipid that has been used to synthesize liposomes. The terminal amine is reactive with an NHS ester compound or carboxylic acid molecule in the presence of activator, such as HATU or EDC.

DSPE-PEG20000-Amine ammonium is an amine derivative of phospholipid-polyethylene glycol, which is used to synthesize solid lipid and thermosensitive liposome nanoparticles for the delivery of anticancer agents. DSPE-PEG20000-Amine ammonium is applicable for cancer research.

DOPE-PEG-Amine (MW 5000) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Amine (MW 5000)can be used in drug delivery research.

DOPE-PEG-Amine (MW 3400) is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DOPE-PEG-Amine (MW 3400)can be used in drug delivery research.

Cholesterol-PEG5000-amine is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG5000-amine can be used in drug delivery research.

Cholesterol-PEG3400-amine is a cholesterol PEG derivative that can form micelles through molecular self-assembly and has a longer half-life in vivo. Cholesterol-PEG3400-amine can be used in drug delivery research.

DMPE-PEG2000-amineTFA is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DMPE-PEG2000-amineTFAcan be used in drug delivery research.

DPPE-PEG2000-amine is a phospholipid. Phospholipids have good biocompatibility and significant amphiphilic characteristics, making them the main and suitable dosage form or excipient in drug formulations, thereby achieving better therapeutic effects. DPPE-PEG2000-aminecan be used in drug delivery research.

16:0 Caproylamine PE is an amide-functionalized lipid with a phosphoethanolamine linked to two palmitic acid tails.

18:1 Caproylamine PE is a amine-functionalized lipid with a phosphoethanolamine linked to two oleic acid tails.

DSPE-PEG10000-Amine ammonium is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG10000-Amine ammonium can be converted into aromatic aldehydes by reacting with acetone-protected aromatic hydrazines on the surface of bovine carbonic anhydrase (BCA) molecules. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

DSPE-PEG5000-Amine ammonium is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. DSPE-PEG5000-Amine ammonium amino group can be converted to aromatic aldehydes that react with acetone-protected aromatic hydrazides on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes produce liposome-Bah-BCA conjugates by forming diaryl hydrazone (BAH) with target enzyme molecules. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

DSPE-PEG-Amine (DSPE-PEG-NH2), MW 3400 ammonium is an amino-functionalized PEGylated phospholipid. It serves not only as a key component for preparing σ receptor-targeted liposomes (such as anisamide-modified lipids) but also as a starting material for synthesizing click chemistry- and tumor-targeted lipids including DSPE-PEG-DBCO (HY-155788) and DSPE-PEG2000-TCO (HY-170704). DSPE-PEG-Amine, MW 3400 ammonium effectively modulates the ζ potential of nanoparticles, enables complexation with nucleic acids or proteins to protect DNA from nuclease degradation, and supports ligand conjugation on the nanoparticle surface. It is used in studies related to DU-145 tumors, breast cancer, and other relevant research.

DSPE-PEG46-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

DSPE-PEG3400-Amine is a class of functionalized polymers composed of a methoxy-terminated polyethylene glycol backbone and a terminal primary amine group. DSPE-PEG3400-Amine serves as an important intermediate for constructing functionalized nanocarriers, modifying proteins or polypeptides, and developing novel drug delivery systems.

Oleoyl-Gly-Lys-(m-PEG11)-NH2 is a PEG-lipid molecule featuring an oleoyl amide linked to a Gly-Lys dipeptide and a methoxy PEG11 chain on the C-terminus of the lysine. The lysine primary amine may be used in a wide variety of reactions with carboxylic acids, NHS esters, and carbonyl groups. The PEG linker provides aqueous solubility.