DPPE-PEG10000-NH2
DPPE-PEG10000-NH2 is a conjugate composed of DPPE, a PEG chain, and a terminal primary amino group (-NH2). The primary amino group in DPPE-PEG10000-NH2 can be covalently linked to functional groups such as carboxylic acids, NHS esters, and isocyanates for targeted modification of liposomes/nanoparticles.
For research use only. We do not sell to patients.
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Biological Activity
-
Chemical Information
- Purity & Documentation
-
Help & FAQs
Biological Activity
The structure of DPPE-PEG-NH2 comprises three key components that work synergistically:
DPPE: Acts as a hydrophobic anchor, responsible for securely embedding the entire molecule into the membrane structure of lipid nanoparticles.
PEG chain: Acts as a hydrophilic spacer arm, forming a hydration layer on the particle surface, reducing non-specific adsorption and immune system recognition and clearance, thus prolonging the carrier's circulation time in vivo.
Primary amino group (-NH2): A reaction interface located at the end of the PEG chain, enabling coupling with various molecules via a mild and efficient chemical method, such as amidation.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
SMILES
CCCCCCCCCCCCCCCC(OC[C@@](COP(O)(OCCNC(OCCN)=O)=O)([H])OC(CCCCCCCCCCCCCCC)=O)=O.[n]
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz