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DSPE-PEG1000-Amine ammonium  (Synonyms: DSPE-PEG1000-NH2 ammonium)

Cat. No.: HY-W440823A Purity: 99.48%
Handling Instructions Technical Support

DSPE-PEG1000-Amine (DSPE-PEG1000-NH2) ammonium is a 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol conjugate with a terminal amino group. DSPE-PEG1000-Amine ammonium can functionalize the surface of PLGA-lecithin-PEG core-shell nanoparticles to introduce positive surface charges. The amino group of DSPE-PEG1000-Amine ammonium can be converted into an aromatic aldehyde to react with the acetone-protected aromatic hydrazide on the surface of bovine carbonic anhydrase (BCA) molecules.

For research use only. We do not sell to patients.

DSPE-PEG1000-Amine ammonium

DSPE-PEG1000-Amine ammonium Chemical Structure

CAS No. : 474922-26-4

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Based on 1 publication(s) in Google Scholar

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Description

DSPE-PEG1000-Amine (DSPE-PEG1000-NH2) ammonium is a 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-polyethylene glycol conjugate with a terminal amino group. DSPE-PEG1000-Amine ammonium can functionalize the surface of PLGA-lecithin-PEG core-shell nanoparticles to introduce positive surface charges. The amino group of DSPE-PEG1000-Amine ammonium can be converted into an aromatic aldehyde to react with the acetone-protected aromatic hydrazide on the surface of bovine carbonic anhydrase (BCA) molecules[1].

In Vitro

DSPE-PEG1000-Amine ammonium functionalizes PLGA-lecithin-PEG core-shell NPs with positive surface charge while maintaining a mean NP size of ~100 nm, under standardized formulation conditions[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1000 (Average)

Formula

(C2H4O)nN2O10P.NH3

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(O[C@@H](COP(OCCNC(OCCOCCN)=O)([O-])=O)COC(CCCCCCCCCCCCCCCCC)=O)CCCCCCCCCCCCCCCCC.[NH4+].[n]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation

Purity: 99.48%

References
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DSPE-PEG1000-Amine ammonium
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