DSPE-PEG5000-Amine
Based on 1 Customer Validation
DSPE-PEG5000-Amine (DSPE-PEG5000-ammonium) is an amino-functionalized PEGylated lipid. DSPE-PEG5000-Amine can be conjugated with chlorin e6 (Ce6) via EDC/NHS coupling. It can also be conjugated with FITC to prepare DSPE-PEG-FITC. DSPE-PEG5000-Amine is applicable to research related to PEGylated lipid functionalization and bioconjugation.
For research use only. We do not sell to patients.
- Purity: 95.0%
- Molecular Weight:5000 (Average)
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
Description
In Vitro
DSPE-PEG5000-Amine (DSPE-PEG5000-ammonium) is conjugated with EDC/NHS-activated Ce6 to obtain DSPE-PEG-Ce6; the conjugation efficiency of Ce6 with DSPE-PEG5000-NH2 is estimated to be 99% by UV-vis spectroscopy[2].
DSPE-PEG5000-Amine (DSPE-PEG5000-Amine ammonium 10 mg; 3 mL of 0.1 M sodium carbonate buffer, pH 9.5) is mixed with FITC (HY-66019) (3.3 mg; 100 μL DMF) and incubated overnight at room temperature to generate DSPE-PEG-FITC; its successful synthesis is confirmed by MALDI-TOF mass spectrometry[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 5000 (Average)
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Color White to off-white
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SMILES
CCCCCCCCCCCCCCCCCC(OCC(COP(OCCNC(OCCOCCN)=O)(O[Na])=O)OC(CCCCCCCCCCCCCCCCC)=O)=O.[n].[MW 5000]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
H2O : 25 mg/mL (Need ultrasonic)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)