2. Immunology/Inflammation
  3. FAP
  4. Faridoxorubicin

Faridoxorubicin (AVA-6000) is a prodrug targeting fibroblast activation protein α (FAPα). Faridoxorubicin releases active doxorubicin through FAPα-mediated cleavage, enhancing intratumoral drug exposure and reducing cardiac toxicity. Faridoxorubicin is promising for research of solid tumors (e.g., colorectal cancer liver metastasis).

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Faridoxorubicin

Faridoxorubicin Estructura química

No. CAS : 1841402-73-0

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Faridoxorubicin Related Antibodies

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Descripciòn

Faridoxorubicin (AVA-6000) is a prodrug targeting fibroblast activation protein α (FAPα). Faridoxorubicin releases active doxorubicin through FAPα-mediated cleavage, enhancing intratumoral drug exposure and reducing cardiac toxicity. Faridoxorubicin is promising for research of solid tumors (e.g., colorectal cancer liver metastasis)[1].

Ensayo clínico
Peso molecular

816.81

Fòrmula

C41H44N4O14
No. CAS
SMILES

OC1=C(C(C2=CC=CC(OC)=C2C3=O)=O)C3=C(O)C4=C1C[C@](C(CO)=O)(O)C[C@@H]4O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O)NC([C@H]6N(CCC6)C([C@@H](C)NC(C7=CC=NC=C7)=O)=O)=O
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Room temperature in continental US; may vary elsewhere.
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Faridoxorubicin Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Faridoxorubicin1841402-73-0AVA-6000AVA6000AVA 6000FAPFibroblast activation proteinFAPαactive doxorubicincardiac toxicitysolid tumorsInhibitorinhibitorinhibit

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Nombre del producto:
Faridoxorubicin
Cat. No.:
HY-177083
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