Ferric pyrophosphate

製品番号: HY-B1648: Data Sheet SDS COA 取扱説明書
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Ferric pyrophosphate is an orally effective anti-inflammatory agent and iron fortifier. Ferric pyrophosphate downregulates the expression of colonic pro-inflammatory cytokines, modulates the intestinal flora, and corrects the dysbiosis associated with iron deficiency anemia (IDA). Ferric pyrophosphate can be used in studies related to iron deficiency anemia.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

Ferric pyrophosphate 構造式

CAS 番号 : 10058-44-3

容量	価格（税別）	在庫状況	数量
25 g	$25	在庫あり	Estimated Time of Arrival: December 31
50 g	$35	在庫あり	Estimated Time of Arrival: December 31
100 g	$50	在庫あり	Estimated Time of Arrival: December 31
500 g	$85	在庫あり	Estimated Time of Arrival: December 31
1 kg	$130	在庫あり	Estimated Time of Arrival: December 31

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生物活性
純度とドキュメンテーション
参考文献
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製品説明

体内実験

Ferric pyrophosphate (FePP) (2-10 mg Fe/kg BW; p.o.; daily; 13 days) effectively alleviates iron deficiency anemia in suckling rats, restores body iron levels without organ accumulation, reduces colonic pro-inflammatory cytokine expression to normal levels, and reverses IDA-induced gut dysbiosis while promoting a more beneficial gut microbiota profile than FeSO₄^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Sprague-Dawley suckling rats (mixed gender, newborn litters adjusted to 12 pups each, iron deficiency anemia induced via maternal low-iron diet during pregnancy)^[1]
Dosage:	2 mg Fe/kg BW; 10 mg Fe/kg BW
Administration:	p.o.; daily; 13 days (postnatal days 2-14)
Result:	Significantly increased body weight of IDA rats compared to the IDA control group at the end of treatment. Significantly down-regulated colonic mRNA expression of pro-inflammatory cytokines IL-6, TNF-α, and IL-1β to levels not significantly different from the normal control group. Reversed IDA-induced gut microbiota structural shifts (high dose), restoring the community structure to resemble the normal control group; increased the relative abundance of beneficial bacteria Bacteroides (from 6.9% to 18.7%) and Akkermansia compared to the IDA control group, and had a greater abundance of these taxa than high-dose FeSO₄.

臨床実験

分子量

745.21

分子式

Fe₄(P₂O₇)3

CAS 番号

10058-44-3

Appearance

Solid

Color

Off-white to light yellow

SMILES

[Fe4(P2O7)3]

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

溶剤 & 溶解度

体外:

H₂O : 50 mg/mL (67.10 mM; Need ultrasonic and warming)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.3419 mL	6.7095 mL	13.4190 mL
5 mM	0.2684 mL	1.3419 mL	2.6838 mL
10 mM	0.1342 mL	0.6710 mL	1.3419 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

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体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

純度とドキュメンテーション

Select Batch:

データシート (272 KB) SDS (394 KB)

COA (306 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Mengxiao Hu, et al. Encapsulated ferric pyrophosphate improves intestinal inflammation and gut flora disorder in suckling rats with iron deficiency anemia. Food Science and Human Wellness 14 (2025) 92502.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.3419 mL	6.7095 mL	13.4190 mL	33.5476 mL
	5 mM	0.2684 mL	1.3419 mL	2.6838 mL	6.7095 mL
	10 mM	0.1342 mL	0.6710 mL	1.3419 mL	3.3548 mL
	15 mM	0.0895 mL	0.4473 mL	0.8946 mL	2.2365 mL
	20 mM	0.0671 mL	0.3355 mL	0.6710 mL	1.6774 mL
	25 mM	0.0537 mL	0.2684 mL	0.5368 mL	1.3419 mL
	30 mM	0.0447 mL	0.2237 mL	0.4473 mL	1.1183 mL
	40 mM	0.0335 mL	0.1677 mL	0.3355 mL	0.8387 mL
	50 mM	0.0268 mL	0.1342 mL	0.2684 mL	0.6710 mL
	60 mM	0.0224 mL	0.1118 mL	0.2237 mL	0.5591 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.