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  3. Amino Acid Derivatives Drug Intermediate
  4. Fmoc-Arg(Pbf)-OH

Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis).

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Fmoc-Arg(Pbf)-OH

Fmoc-Arg(Pbf)-OH Estructura química

No. CAS : 154445-77-9

Tamaño Precio Stock Cantidad
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Solution
10 mM * 1 mL in DMSO En stock
Solid
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Fmoc-Arg(Pbf)-OH Related Antibodies

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Descripciòn

Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis)[1][2][3].

In Vitro

Fmoc-Arg(Pbf)-OH (1 mM) can be used as a model Fmoc-amino acid to establish a peptide quantification method: each Fmoc group generates a dibenzofuran (DBF) molecule, and the concentration of DBF directly reflects the concentration of the peptide[2].
Fmoc-Arg(Pbf)-OH can be used to protect arginine and to synthesize the novel polymer NAC-HP-β-CD-Arg, which enhances cell penetration and enables efficient delivery of oral insulin[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Fmoc-Arg(Pbf)-OH Related Antibodies
Peso molecular

648.77

Fòrmula

C34H40N4O7S
No. CAS
Appearance

Solid

Color

White to off-white

Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvente y solubilidad
In Vitro: 

DMSO : 100 mg/mL (154.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.5414 mL 7.7069 mL 15.4138 mL
5 mM 0.3083 mL 1.5414 mL 3.0828 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Pureza y Documentación

Purity: 99.97%

SDS (393 KB)

COA (249 KB) HNMR (137 KB) RP-HPLC (233 KB) LCMS (322 KB)

Instrucciones de manejo (2659 KB)
Referencias

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.5414 mL 7.7069 mL 15.4138 mL 38.5345 mL
5 mM 0.3083 mL 1.5414 mL 3.0828 mL 7.7069 mL
10 mM 0.1541 mL 0.7707 mL 1.5414 mL 3.8534 mL
15 mM 0.1028 mL 0.5138 mL 1.0276 mL 2.5690 mL
20 mM 0.0771 mL 0.3853 mL 0.7707 mL 1.9267 mL
25 mM 0.0617 mL 0.3083 mL 0.6166 mL 1.5414 mL
30 mM 0.0514 mL 0.2569 mL 0.5138 mL 1.2845 mL
40 mM 0.0385 mL 0.1927 mL 0.3853 mL 0.9634 mL
50 mM 0.0308 mL 0.1541 mL 0.3083 mL 0.7707 mL
60 mM 0.0257 mL 0.1284 mL 0.2569 mL 0.6422 mL
80 mM 0.0193 mL 0.0963 mL 0.1927 mL 0.4817 mL
100 mM 0.0154 mL 0.0771 mL 0.1541 mL 0.3853 mL
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Fmoc-Arg(Pbf)-OH Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fmoc-Arg(Pbf)-OH154445-77-9Amino Acid DerivativesDrug IntermediateDrug Iintermediatearginine derivativeFmocbuilding blocksolid-phase peptide synthesisSPPSInhibitorinhibitorinhibit

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Nombre del producto:
Fmoc-Arg(Pbf)-OH
Cat. No.:
HY-Y1636
Cantidad:
MCE Japan Authorized Agent:

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