Fmoc-Arg(Pbf)-OH-¹³C₆,¹⁵N₄

Name: Fmoc-Arg(Pbf)-OH- 13 C 6 , 15 N 4
Brand: MedChemExpress
SKU: HY-Y1636S
Rating: 4.5 (0 reviews)

Cat. No.: HY-Y1636S Purity: 97.7%: Data Sheet
COA

SDS
Handling Instructions
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Fmoc-Arg(Pbf)-OH-¹³C₆,¹⁵N₄ is the ¹³C-labeled and ¹⁵N-labeled Fmoc-Arg(Pbf)-OH (HY-Y1636). Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis).

For research use only. We do not sell to patients.

Fmoc-Arg(Pbf)-OH-<sup>13</sup>C<sub>6</sub>,<sup>15</sup>N<sub>4</sub>

Fmoc-Arg(Pbf)-OH-¹³C₆,¹⁵N₄ Chemical Structure

CAS No. : 1217461-89-6

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	Get quote	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Other Forms of Fmoc-Arg(Pbf)-OH-¹³C₆,¹⁵N₄:

Fmoc-Arg(Pbf)-OH In-stock
Fmoc-Arg(Pbf)-OH-¹³C₆ Get quote

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Purity & Documentation
References
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Description

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

658.70

Formula

C₂₈¹³C₆H₄₀¹⁵N₄O₇S

CAS No.

1217461-89-6

Unlabeled CAS

154445-77-9

Appearance

Solid

Color

White to off-white

SMILES

O=S([15NH][13C]([15NH][13CH2][13CH2][13CH2][13C@@H]([13C](O)=O)[15NH]C(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)=[15NH])(C4=C(C)C(C)=C(OC(C)(C5)C)C5=C4C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (151.81 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.5181 mL	7.5907 mL	15.1814 mL
5 mM	0.3036 mL	1.5181 mL	3.0363 mL
10 mM	0.1518 mL	0.7591 mL	1.5181 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 98.3%

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Data Sheet (273 KB) SDS (394 KB)

COA (250 KB)

Handling Instructions (2659 KB)

References

[1]. Beatriz G, et al. Successful development of a method for the incorporation of Fmoc-Arg (Pbf)-OH in solid-phase peptide synthesis using N-butylpyrrolidinone (NBP) as solvent. Green Chemistry, 2020, 22(10): 3162-3169.

[2]. Wojciechowski JP, et al. A Facile Method to Quantify Synthetic Peptide Concentrations on Biomaterials. ACS Appl Mater Interfaces. 2024 Sep 18;16(37):49880-49888. [Content Brief]

[3]. Li S, et al. Inclusion complex based on N-acetyl-L-cysteine and arginine modified hydroxypropyl-β-cyclodextrin for oral insulin delivery. Carbohydr Polym. 2021 Jan 15;252:117202. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.5181 mL	7.5907 mL	15.1814 mL	37.9535 mL
	5 mM	0.3036 mL	1.5181 mL	3.0363 mL	7.5907 mL
	10 mM	0.1518 mL	0.7591 mL	1.5181 mL	3.7954 mL
	15 mM	0.1012 mL	0.5060 mL	1.0121 mL	2.5302 mL
	20 mM	0.0759 mL	0.3795 mL	0.7591 mL	1.8977 mL
	25 mM	0.0607 mL	0.3036 mL	0.6073 mL	1.5181 mL
	30 mM	0.0506 mL	0.2530 mL	0.5060 mL	1.2651 mL
	40 mM	0.0380 mL	0.1898 mL	0.3795 mL	0.9488 mL
	50 mM	0.0304 mL	0.1518 mL	0.3036 mL	0.7591 mL
	60 mM	0.0253 mL	0.1265 mL	0.2530 mL	0.6326 mL
	80 mM	0.0190 mL	0.0949 mL	0.1898 mL	0.4744 mL
	100 mM	0.0152 mL	0.0759 mL	0.1518 mL	0.3795 mL