Fmoc-Arg(Pbf)-OH
Based on 1 Customer Validation
Fmoc-Arg(Pbf)-OH is an arginine derivative containing amine protecting group Fmoc. Fmoc-Arg(Pbf)-OH is a building block for the introduction of Arg into SPPS (Solid-Phase Peptide Synthesis).
For research use only. We do not sell to patients.
- Purity: 99.94%
- CAS No.: 154445-77-9
- Formula: C34H40N4O7S
- Molecular Weight:648.77
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Fmoc-Arg(Pbf)-OH (1 mM) can be used as a model Fmoc-amino acid to establish a peptide quantification method: each Fmoc group generates a dibenzofuran (DBF) molecule, and the concentration of DBF directly reflects the concentration of the peptide[2].
Fmoc-Arg(Pbf)-OH can be used to protect arginine and to synthesize the novel polymer NAC-HP-β-CD-Arg, which enhances cell penetration and enables efficient delivery of oral insulin[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 154445-77-9
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Appearance Solid
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Molecular Weight 648.77
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Formula C34H40N4O7S
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Color White to off-white
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (154.14 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[2]. Wojciechowski JP, et al. A Facile Method to Quantify Synthetic Peptide Concentrations on Biomaterials. ACS Appl Mater Interfaces. 2024 Sep 18;16(37):49880-49888. [Content Brief]
[3]. Li S, et al. Inclusion complex based on N-acetyl-L-cysteine and arginine modified hydroxypropyl-β-cyclodextrin for oral insulin delivery. Carbohydr Polym. 2021 Jan 15;252:117202. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5414 mL | 7.7069 mL | 15.4138 mL | 38.5345 mL |
| 5 mM | 0.3083 mL | 1.5414 mL | 3.0828 mL | 7.7069 mL | |
| 10 mM | 0.1541 mL | 0.7707 mL | 1.5414 mL | 3.8534 mL | |
| 15 mM | 0.1028 mL | 0.5138 mL | 1.0276 mL | 2.5690 mL | |
| 20 mM | 0.0771 mL | 0.3853 mL | 0.7707 mL | 1.9267 mL | |
| 25 mM | 0.0617 mL | 0.3083 mL | 0.6166 mL | 1.5414 mL | |
| 30 mM | 0.0514 mL | 0.2569 mL | 0.5138 mL | 1.2845 mL | |
| 40 mM | 0.0385 mL | 0.1927 mL | 0.3853 mL | 0.9634 mL | |
| 50 mM | 0.0308 mL | 0.1541 mL | 0.3083 mL | 0.7707 mL | |
| 60 mM | 0.0257 mL | 0.1284 mL | 0.2569 mL | 0.6422 mL | |
| 80 mM | 0.0193 mL | 0.0963 mL | 0.1927 mL | 0.4817 mL | |
| 100 mM | 0.0154 mL | 0.0771 mL | 0.1541 mL | 0.3853 mL |
Fmoc-Arg(Pbf)-OH Related Classifications
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