2. GPCR/G Protein Neuronal Signaling
  3. Neurokinin Receptor
  4. GR 64349

GR 64349 is a potent and highly selective NK2 receptor peptide agonist, with an EC50 of 3.7 nM in rat colon. GR 64349 exhibits selectivity >1000 and >300-fold with respect to NK1 and NK3 receptors, respectively.

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Custom Peptide Synthesis

GR 64349

GR 64349 화학구조

CAS No. : 137593-52-3

사이즈 가격 재고 수량
1 mg 해외재고보유
5 mg 해외재고보유
10 mg   견적 받기  
50 mg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

Other Forms of GR 64349:

GR 64349 Related Antibodies

Top Publications Citing Use of Products

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NK1R NK2R NK3R

  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

GR 64349 is a potent and highly selective NK2 receptor peptide agonist, with an EC50 of 3.7 nM in rat colon. GR 64349 exhibits selectivity >1000 and >300-fold with respect to NK1 and NK3 receptors, respectively[1][2].

IC50 & Target[1]

NK2R

 

분자량

921.11

화학식

C42H68N10O11S
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Lys-Asp-Ser-Phe-Val-{Aaa}-Leu-Met-NH2
Sequence Shortening

KDSFV{Aaa}LM-NH2
선적

Room temperature in continental US; may vary elsewhere.
보관

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

용액&용해도
In Vitro: 

H2O : ≥ 50 mg/mL (54.28 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0856 mL 5.4282 mL 10.8565 mL
5 mM 0.2171 mL 1.0856 mL 2.1713 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
순도&문서
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.0856 mL 5.4282 mL 10.8565 mL 27.1412 mL
5 mM 0.2171 mL 1.0856 mL 2.1713 mL 5.4282 mL
10 mM 0.1086 mL 0.5428 mL 1.0856 mL 2.7141 mL
15 mM 0.0724 mL 0.3619 mL 0.7238 mL 1.8094 mL
20 mM 0.0543 mL 0.2714 mL 0.5428 mL 1.3571 mL
25 mM 0.0434 mL 0.2171 mL 0.4343 mL 1.0856 mL
30 mM 0.0362 mL 0.1809 mL 0.3619 mL 0.9047 mL
40 mM 0.0271 mL 0.1357 mL 0.2714 mL 0.6785 mL
50 mM 0.0217 mL 0.1086 mL 0.2171 mL 0.5428 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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GR 64349 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GR 64349137593-52-3GR64349GR-64349Neurokinin ReceptorNK receptorTachykinin receptorInhibitorinhibitorinhibit

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상품명:
GR 64349
Cat. No.:
HY-P1278
수량:
MCE Japan Authorized Agent:

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