h-FTAA

Cat. No.: HY-177906: Ficha de datos
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h-FTAA is a luminescent conjugated oligothiophene (LCO) probe. h-FTAA can selectively bind to amyloid protein aggregates (such as Aβ plaques) and distinguish different conformations of the protein aggregates through changes in fluorescence signals. h-FTAA significantly reduces the neurotoxicity of Aβ1-42 and the Arctic mutant Aβ (AβArc), thereby protecting SH-SY5Y neuroblastoma cells. h-FTAA can be used to dynamically track the formation and maturation process of Aβ plaques.

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h-FTAA Estructura química

No. CAS : 1352477-26-9

Tamaño	Stock	Cantidad
5 mg	Obtener un presupuesto 9 - 11 weeks 8 - 10 weeks 10 - 12 weeks 9 - 11 weeks	Estimated Time of Arrival: December 31
10 mg	Obtener un presupuesto 9 - 11 weeks 8 - 10 weeks 10 - 12 weeks 9 - 11 weeks	Estimated Time of Arrival: December 31
25 mg	Obtener un presupuesto 9 - 11 weeks 8 - 10 weeks 10 - 12 weeks 9 - 11 weeks	Estimated Time of Arrival: December 31
50 mg	Obtener un presupuesto 9 - 11 weeks 8 - 10 weeks 10 - 12 weeks 9 - 11 weeks	Estimated Time of Arrival: December 31
100 mg	Obtener un presupuesto 9 - 11 weeks 8 - 10 weeks 10 - 12 weeks 9 - 11 weeks	Estimated Time of Arrival: December 31
200 mg	Obtener un presupuesto
500 mg	Obtener un presupuesto

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Descripciòn	h-FTAA is a luminescent conjugated oligothiophene (LCO) probe. h-FTAA can selectively bind to amyloid protein aggregates (such as Aβ plaques) and distinguish different conformations of the protein aggregates through changes in fluorescence signals. h-FTAA significantly reduces the neurotoxicity of Aβ1-42 and the Arctic mutant Aβ (AβArc), thereby protecting SH-SY5Y neuroblastoma cells. h-FTAA can be used to dynamically track the formation and maturation process of Aβ plaques^[1]^[2].
Peso molecular	780.97
Fòrmula	C₃₄H₂₀O₈S₇
No. CAS	1352477-26-9
SMILES	O=C(C1=CC=C(C2=CC=C(C3=CC(CC(O)=O)=C(C4=CC=C(C5=C(CC(O)=O)C=C(C6=CC=C(C7=CC=C(C(O)=O)S7)S6)S5)S4)S3)S2)S1)O
Envío	Room temperature in continental US; may vary elsewhere.
Almacenamiento	Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación	Ficha de datos (268 KB) SDS (252 KB) Instrucciones de manejo (2659 KB)
Referencias	[1]. Sandin L, et al. The Luminescent Conjugated Oligothiophene h-FTAA Attenuates the Toxicity of Different Aβ Species. Biochemistry. 2021 Sep 21;60(37):2773-2780. [Content Brief] [2]. Wood JI, et al. Isotope-encoded spatial biology identifies plaque-age-dependent maturation and synaptic loss in an Alzheimer's disease mouse model. Nat Commun. 2025 Sep 1;16(1):8170. [Content Brief]

h-FTAA Related Classifications

Neurological Disease

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

h-FTAA1352477-26-9Fluorescent DyeAmyloid-ββ-amyloid peptideAβAbetaLuminescent conjugated oligothiophenesAβ toxicityamyloid aggregationAlzheimer's diseasespectral imagingoligomer stabilizationneuroprotectionInhibitorinhibitorinhibit

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h-FTAA

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h-FTAA Related Classifications

Calculadora de molaridad

Calculadora de dilución

The molarity calculator equation

The dilution calculator equation

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