HS-PEG3-CH2CH2NH2 (Synonyms: Thiol-PEG3-amine)

Cat. No.: HY-130871: Ficha de datos
COA

SDS
Instrucciones de manejo
FAQs
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HS-PEG3-CH2CH2NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (HS-PEG3-CH2CH2NH2 hydrochloride) usually boasts enhanced water solubility and stability.

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HS-PEG3-CH2CH2NH2 Estructura química

No. CAS : 1189760-69-7

Tamaño	Precio	Stock
25 mg		Pide un presupuesto y un plazo de entrega
50 mg		Pide un presupuesto y un plazo de entrega
100 mg		Pide un presupuesto y un plazo de entrega

* Seleccione Cantidad antes de agregar artículos.

This product is a controlled substance and not for sale in your territory.

Other In-stock Forms of HS-PEG3-CH2CH2NH2:

HS-PEG3-CH2CH2NH2 hydrochloride

Other Forms of HS-PEG3-CH2CH2NH2:

HS-PEG3-CH2CH2NH2 hydrochloride In-stock

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Ver todos los productos específicos de isoformas PROTAC Linkers:

Ver todas las isoformas

PEG Linkers Alkyl-Chain Linkers Alkyl/ether Linkers

Actividad biológica
Pureza y Documentación
Referencias
Revisión del cliente

Descripciòn

HS-PEG3-CH2CH2NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs^[1].

IC₅₀ & Target

PEGs

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Peso molecular

209.31

Fòrmula

C₈H₁₉NO₃S

No. CAS

1189760-69-7

Appearance

Viscous Liquid

Color

Light yellow to yellow

SMILES

NCCOCCOCCOCCS

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Pureza y Documentación

Purity: 97.0%

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Ficha de datos (262 KB) SDS (624 KB)

COA (240 KB) HNMR (132 KB) MS (78 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 [Content Brief]

HS-PEG3-CH2CH2NH2 Related Classifications

Calculadora de molaridad
Calculadora de dilución

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HS-PEG3-CH2CH2NH21189760-69-7Thiol-PEG3-aminePROTAC LinkersInhibitorinhibitorinhibit

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