1. Metabolic Enzyme/Protease
  2. Ser/Thr Protease
  3. HTRA1-IN-1

HTRA1-IN-1 is a potent and selective high temperature requirement A serine peptid 1 (HTRA1) inhibitor with an IC50 of 13 nM. HTRA1-IN-1 can be used for the research of HTRA1-related diseases, such as age-related macular degeneration (AMD), osteoarthritis, and rheumatoid arthritis.

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HTRA1-IN-1

HTRA1-IN-1 화학구조

CAS No. : 3052552-04-9

사이즈 가격 재고 수량
1 mg 해외재고보유
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 해외재고보유
50 mg   견적 받기  
100 mg   견적 받기  

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제품 설명

HTRA1-IN-1 is a potent and selective high temperature requirement A serine peptid 1 (HTRA1) inhibitor with an IC50 of 13 nM. HTRA1-IN-1 can be used for the research of HTRA1-related diseases, such as age-related macular degeneration (AMD), osteoarthritis, and rheumatoid arthritis[1].

IC50 & Target

HTRA1

13 nM (IC50)

In Vitro

HTRA1-IN-1 (Compound 17) (1 μM) shows high selectivity for HTRA1 over a panel of 35 human proteases, with an IC50 13 nM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

583.95

화학식

C31H43BClN3O5

CAS No.
Appearance

Solid

Color

White to yellow

SMILES

O=C(N[C@@H](CC1=CC=CC(Cl)=C1)C(N[C@@H](CC(C)C)C(N[C@@H](C2CCC2)B(O)O)=O)=O)C(C)(C)CC3=CC=CC=C3

선적

Room temperature in continental US; may vary elsewhere.

보관
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
순도&문서
References
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This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
HTRA1-IN-1
Cat. No.:
HY-163690
수량:
MCE Japan Authorized Agent: