2. Others Neuronal Signaling Membrane Transporter/Ion Channel
  3. Reference Standards Cholinesterase (ChE) Potassium Channel Sodium Channel
  4. Ipidacrine (Standard)

Ipidacrine (Standard)  (Synonyms: NIK-247 free base (Standard); Amiridine free base (Standard))

製品番号: HY-W027553R 純度: 98%
取扱説明書 Technical Support

Ipidacrine (Standard) is the analytical reference standard of Ipidacrine. This product is used for research and analytical applications. Ipidacrine is orally active and blood-brain-barrier-penetrant AChE and BuChE inhibitors with IC50 values of 1 μM and 1.9 μM, respectively, which is also a partial agonist of M2-cholinergic receptors and a reversible cholinesterase inhibitor. Ipidacrine has a stimulating effect on neuromuscular transmission and excitation along the nerve fibres with a moderately anti-pain effect. Ipidacrine is an aminopyridines and is structurally similar to Tacrine (HY-111338). Ipidacrine is effective in various amnesia models, improves erectile function and inhibits K+ and Na+-channels in the neuronal membrane in diabetic rats. Ipidacrine is promising for research of Alzheimer’s disease, ischaemic stroke, idiopathic neuropathy of the facial nerve, diabetes mellitus-induced erectile dysfunction and other deficits in central or peripheral cholinergic deseases.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

Ipidacrine (Standard)

Ipidacrine (Standard) 構造式

CAS 番号 : 62732-44-9

容量 価格（税別） 在庫状況 数量
10 mg $30 お問い合わせ 5 - 6 weeks 4 - 5 weeks 6 - 7 weeks 5 - 6 weeks
25 mg $50 お問い合わせ 5 - 6 weeks 4 - 5 weeks 6 - 7 weeks 5 - 6 weeks
50 mg $70 お問い合わせ 5 - 6 weeks 4 - 5 weeks 6 - 7 weeks 5 - 6 weeks
100 mg $100 お問い合わせ 5 - 6 weeks 4 - 5 weeks 6 - 7 weeks 5 - 6 weeks
250 mg $180 お問い合わせ 5 - 6 weeks 4 - 5 weeks 6 - 7 weeks 5 - 6 weeks
500 mg $270 お問い合わせ 5 - 6 weeks 4 - 5 weeks 6 - 7 weeks 5 - 6 weeks
1 g   お問い合わせ  
5 g   お問い合わせ  
Synthetic products have potential research and development risk.

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

Top Publications Citing Use of Products

  • Product Information

  • 純度とドキュメンテーション

  • カスタマーレビュー

製品説明

Ipidacrine (Standard) is the analytical reference standard of Ipidacrine. This product is used for research and analytical applications. Ipidacrine is orally active and blood-brain-barrier-penetrant AChE and BuChE inhibitors with IC50 values of 1 μM and 1.9 μM, respectively, which is also a partial agonist of M2-cholinergic receptors and a reversible cholinesterase inhibitor. Ipidacrine has a stimulating effect on neuromuscular transmission and excitation along the nerve fibres with a moderately anti-pain effect. Ipidacrine is an aminopyridines and is structurally similar to Tacrine (HY-111338). Ipidacrine is effective in various amnesia models, improves erectile function and inhibits K+ and Na+-channels in the neuronal membrane in diabetic rats. Ipidacrine is promising for research of Alzheimer’s disease, ischaemic stroke, idiopathic neuropathy of the facial nerve, diabetes mellitus-induced erectile dysfunction and other deficits in central or peripheral cholinergic deseases.

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
分子量

188.27

分子式

C12H16N2
CAS 番号
SMILES

NC1=C(CCC2)C2=NC3=C1CCCC3
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Ipidacrine (Standard) Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質量   濃度   体積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

一般には略語で表示されます：C1V1 = C2V2

濃度 （開始） × 体積 （開始） = 濃度 （終了） × 体積 （終了）
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ipidacrine (Standard)62732-44-9NIK-247 free base (Standard) Amiridine free base (Standard)Reference StandardsCholinesterase (ChE)Potassium ChannelSodium ChannelKcsANa channelsNa+ channelsorally activebrain-penetrantAChEBuChEM2-cholinergic receptorsanti-pain effectK+ and Na+-channelsAlzheimer’s diseaseischaemic strokediabetes mellitus-induced erectile dysfunctionother deficits in central or peripheral cholinergic deseasesInhibitorinhibitorinhibit

最近チェックした製品:

オンラインお問い合わせ

Your information is safe with us. * Required Fields.

製品名

  

カスタマ需要量 *

お名前 *

 

タイトル

メールアドレス *

 

電話番号 *

デパートメント

 

組纖名 *

市区町村

都道府県

国或いは地域 *

      

必ず会社名を記載ください。個人への返信は行いません。

備考

バルクお問い合わせ

Inquiry Information

製品名:
Ipidacrine (Standard)
製品番号:
HY-W027553R
数量:
MCE 日本正規代理店:

カスタマーレビュー

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

製品名

  

Lot #

お名前 *

 

メールアドレス *

電話番号 *

 

部門 *

組纖名 *

 

国或いは地域 *

備考

Request for HNMR Report

We have received your request and will respond to you as soon as possible.