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  3. Iron(II) succinate

Iron(II) succinate (Ferrous succinate) is an orally active and organic acid iron supplement (ferrous salt). Iron(II) succinate improves hematological parameters in iron-deficiency anemia rats, including hemoglobin, red blood cells, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration. Iron(II) succinate increases serum ferritin, serum iron levels, and transferrin saturation, while decreasing total iron-binding capacity in iron-deficiency anemia rats. Iron(II) succinate reduces the elevated heart, spleen, and kidney coefficients, and increases the decreased liver coefficient in iron-deficiency anemia rats. Iron(II) succinate replenishes the depleted iron content in the liver and spleen of iron-deficiency anemia rats. Iron(II) succinate can be used for the research of iron-deficiency anemia.

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Iron(II) succinate

Iron(II) succinate Estructura química

No. CAS : 10030-90-7

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Descripciòn

Iron(II) succinate (Ferrous succinate) is an orally active and organic acid iron supplement (ferrous salt). Iron(II) succinate improves hematological parameters in iron-deficiency anemia rats, including hemoglobin, red blood cells, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration. Iron(II) succinate increases serum ferritin, serum iron levels, and transferrin saturation, while decreasing total iron-binding capacity in iron-deficiency anemia rats. Iron(II) succinate reduces the elevated heart, spleen, and kidney coefficients, and increases the decreased liver coefficient in iron-deficiency anemia rats. Iron(II) succinate replenishes the depleted iron content in the liver and spleen of iron-deficiency anemia rats. Iron(II) succinate can be used for the research of iron-deficiency anemia[1].

In Vivo

Iron(II) succinate (15 mg Fe/kg/d; intragastric administration; once daily; for 10 consecutive days) restores the hematological indices, serum biochemical parameters, organ coefficients, and hepatic/splenic iron contents of rats with iron deficiency anemia to levels close to or completely consistent with those of normal controls[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Sprague-Dawley (SD) (male, 4-6 weeks of age, fed Fe-restricted (10 ppm) diet and bled twice weekly for 26 days to induce IDA)[1]
Dosage: 15 mg Fe/kg/d
Administration: intragastrically; once daily; 10 days
Result: Increased body weight by 13% compared to untreated IDA rats.
Increased Hb, RBC, HCT, MCV, MCH, and MCHC; all values were comparable to normal control levels except MCV which was slightly lower than normal control.
Increased SF, SI, and TS; decreased TIBC, with values near normal control levels.
Increased liver iron content; spleen iron content, liver iron content approached normal control levels.
Peso molecular

172.93

Fòrmula

C4H5FeO4

No. CAS
SMILES

O=C(CCC(O[Fe])=O)O

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Nombre del producto:
Iron(II) succinate
Cat. No.:
HY-W581820
Cantidad:
MCE Japan Authorized Agent: