Iso-PPADS tetrasodium

Art. -Nr.: HY-101077: Data Sheet Handling Instructions
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Iso-PPADS tetrasodium is a P2X-purinoceptor antagonist. Iso-PPADS tetrasodium inhibits P2X1 and P2X3 receptor with IC₅₀s of 43 nM and 84 nM. Iso-PPADS tetrasodium is protective against ventilator-induced brain injury (VIBI).

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Iso-PPADS tetrasodium Chemische Struktur

CAS. Nr. : 207572-67-6

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5 mg	Angebot einholen 3 - 4 Weeks 4 - 5 weeks 5 - 6 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
10 mg	Angebot einholen 3 - 4 Weeks 4 - 5 weeks 5 - 6 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 mg	Angebot einholen
100 mg	Angebot einholen

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Other Forms of Iso-PPADS tetrasodium:

PPADS tetrasodium In-stock

Spezialitätsempfehlungen

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Alle P2X Receptor Isoform-spezifische Produkte anzeigen:

Alle Isoformen anzeigen

P2X1 Receptor P2X2 Receptor P2X3 Receptor P2X4 Receptor P2X7 Receptor

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Beschreibung	Iso-PPADS tetrasodium is a P2X-purinoceptor antagonist. Iso-PPADS tetrasodium inhibits P2X1 and P2X3 receptor with IC₅₀s of 43 nM and 84 nM. Iso-PPADS tetrasodium is protective against ventilator-induced brain injury (VIBI)^[1]^[2].
IC₅₀ & Target	43 nM and 84 nM (P2X1 and P2X3 receptor)^[2]
Molekulargewicht	599.30
Formel	C₁₄H₁₀N₃Na₄O₁₂PS₂
CAS. Nr.	207572-67-6
SMILES	O=S(C1=CC=C(S(=O)(O[Na])=O)C=C1/N=N/C2=NC(C)=C(O)C(C=O)=C2COP(O[Na])(O[Na])=O)(O[Na])=O
Versand	Room temperature in continental US; may vary elsewhere.
Speicherung	Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation	Data Sheet (274 KB) Handling Instructions (2659 KB)
Verweise	[1]. González-López A, et al. Lung Purinoceptor Activation Triggers Ventilator-Induced Brain Injury. Crit Care Med. 2019 Nov;47(11):e911-e918. [Content Brief] [2]. Brown SG, et al. Actions of a Series of PPADS Analogs at P2X1 and P2X3 Receptors. Drug Dev Res. 2001 Aug;53(4):281-291. [Content Brief]