Lactate Dehydrogenase (LDH), Bovine Heart  (Synonyms: LAD, LD, L-LDH, (S)-Lactate: NAD+ oxidoreductase)

Lactate Dehydrogenase (LDH), Bovine Heart (LAD) is an oxidoreductase that catalyzes the reversible conversion between lactate and pyruvate. Lactate Dehydrogenase (LDH), Bovine Heart is mainly used in life science research, tissue damage diagnosis, and as an enzyme marker^[1][2][3].

Lactate Dehydrogenase (LDH), Bovine Heart is released into the blood when myocardial cells are damaged due to foot-and-mouth disease. An increase in its activity can serve as a non-specific diagnostic indicator for tissue damage^[1].
Lactate Dehydrogenase (LDH), Bovine Heart can form complex interactions with lipids on the cell membrane. This binding is regulated by the cellular microenvironment (pH, ionic strength, metabolite concentration), thereby affecting its localization within the cell and catalytic activity^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

9001-60-9

Solid

White to off-white

[Lactate Dehydrogenase (LDH), Bovine Heart]

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• [1]. Lactate Dehydrogenase (LDH), Bovine Heart  [Content Brief]

  [2]. Deka P,et al. Foot-and-mouth disease-associated myocarditis is age dependent in suckling calves. Sci Rep. 2024 May 4;14(1):10289.  [Content Brief]

  [3]. Farhana A, Lappin SL. Biochemistry, Lactate Dehydrogenase. 2023 May 1. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–.  [Content Brief]