Lactofen

Cat. No.: HY-W019880 Purity: 98.06%: Data Sheet
COA

SDS
Handling Instructions
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Lactofen is a herbicide that targets dicotyledonous weeds and causes oxidative stress, activating the expression of chalcone synthase and chalcone reductase.

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Lactofen 화학구조

CAS No. : 77501-63-4

사이즈	재고	수량

무료 샘플 (0.1 - 0.2 mg)	지금 신청하기
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	해외재고보유	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	해외재고보유	Estimated Time of Arrival: December 31
Solid
100 mg	해외재고보유	Estimated Time of Arrival: December 31
500 mg	해외재고보유	Estimated Time of Arrival: December 31
1 g	견적 받기
5 g	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

Lactofen is a herbicide that targets dicotyledonous weeds and causes oxidative stress, activating the expression of chalcone synthase and chalcone reductase^[1].

분자량

461.77

화학식

C₁₉H₁₅ClF₃NO₇

CAS No.

77501-63-4

Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(C1=CC(OC2=CC=C(C(F)(F)F)C=C2Cl)=CC=C1[N+]([O-])=O)OC(C)C(OCC)=O

선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

용액&용해도

In Vitro:

DMSO : 100 mg/mL (216.56 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.1656 mL	10.8279 mL	21.6558 mL
5 mM	0.4331 mL	2.1656 mL	4.3312 mL
10 mM	0.2166 mL	1.0828 mL	2.1656 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: 5 mg/mL (10.83 mM); Suspended solution; Need ultrasonic

This protocol yields a suspended solution of 5 mg/mL. Suspended solution can be used for oral and intraperitoneal injection.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

순도&문서

Purity: 98.06%

Select Batch:

Data Sheet (269 KB) SDS (597 KB)

COA (246 KB) HNMR (184 KB) LCMS (103 KB)

Handling Instructions (2659 KB)

References

[1]. Graham MY. The diphenylether herbicide lactofen induces cell death and expression of defense-related genes in soybean. Plant Physiol. 2005 Dec;139(4):1784-94. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.1656 mL	10.8279 mL	21.6558 mL	54.1395 mL
	5 mM	0.4331 mL	2.1656 mL	4.3312 mL	10.8279 mL
	10 mM	0.2166 mL	1.0828 mL	2.1656 mL	5.4140 mL
	15 mM	0.1444 mL	0.7219 mL	1.4437 mL	3.6093 mL
	20 mM	0.1083 mL	0.5414 mL	1.0828 mL	2.7070 mL
	25 mM	0.0866 mL	0.4331 mL	0.8662 mL	2.1656 mL
	30 mM	0.0722 mL	0.3609 mL	0.7219 mL	1.8047 mL
	40 mM	0.0541 mL	0.2707 mL	0.5414 mL	1.3535 mL
	50 mM	0.0433 mL	0.2166 mL	0.4331 mL	1.0828 mL
	60 mM	0.0361 mL	0.1805 mL	0.3609 mL	0.9023 mL
	80 mM	0.0271 mL	0.1353 mL	0.2707 mL	0.6767 mL
	100 mM	0.0217 mL	0.1083 mL	0.2166 mL	0.5414 mL

Lactofen Related Classifications

Others

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lactofen77501-63-4HerbicideInhibitorinhibitorinhibit

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Lactofen

Lactofen Related Antibodies

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