2. Apoptosis
  3. Apoptosis
  4. Lepidozin G

Lepidozin G inhibits the growth of a panel of cancer cell lines with IC50 values ranging from 4.2 ± 0.2 to 5.7 ± 0.5 μM. Lepidozin G induces PC-3 cell death via mitochondrial-related apoptosis.

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Lepidozin G

Lepidozin G Chemical Structure

CAS No. : 2869125-43-7

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Lepidozin G Related Antibodies

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Description

Lepidozin G inhibits the growth of a panel of cancer cell lines with IC50 values ranging from 4.2 ± 0.2 to 5.7 ± 0.5 μM. Lepidozin G induces PC-3 cell death via mitochondrial-related apoptosis.

Cellular Effect
Cell Line Type Value Description References
A549 IC50
4.4 μM
Compound: 7
Cytotoxicity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
[PMID: 34797067]
NCI-H3255 IC50
5.7 μM
Compound: 7
Cytotoxicity against human NCI-H3255 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Cytotoxicity against human NCI-H3255 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
[PMID: 34797067]
NCI-H446 IC50
5 μM
Compound: 7
Cytotoxicity against human NCI-H446 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Cytotoxicity against human NCI-H446 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
[PMID: 34797067]
PC-3 IC50
4.2 μM
Compound: 7
Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
[PMID: 34797067]
Masse moléculaire

472.70

Formule

C30H48O4
CAS No.
SMILES

CC(C(CC[C@@H](C)[C@@]1([H])[C@H](O)C[C@@]2(C)[C@]3([H])CC[C@]4([H])[C@@](CC[C@H](O)C4(C)C)(O)CC3=CC[C@@]21C)=O)=C
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
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Lepidozin G Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lepidozin G2869125-43-7ApoptosisInhibitorinhibitorinhibit

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