Lepidozin G

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Lepidozin G inhibits the growth of a panel of cancer cell lines with IC₅₀ values ranging from 4.2 ± 0.2 to 5.7 ± 0.5 μM. Lepidozin G induces PC-3 cell death via mitochondrial-related apoptosis.

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Lepidozin G 화학구조

CAS No. : 2869125-43-7

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Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	4.4 μM Compound: 7	Cytotoxicity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 34797067]
NCI-H3255	IC₅₀	5.7 μM Compound: 7	Cytotoxicity against human NCI-H3255 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Cytotoxicity against human NCI-H3255 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 34797067]
NCI-H446	IC₅₀	5 μM Compound: 7	Cytotoxicity against human NCI-H446 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Cytotoxicity against human NCI-H446 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 34797067]
PC-3	IC₅₀	4.2 μM Compound: 7	Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 34797067]

분자량

472.70

화학식

C₃₀H₄₈O₄

CAS No.

2869125-43-7

SMILES

CC(C(CC[C@@H](C)[C@@]1([H])[C@H](O)C[C@@]2(C)[C@]3([H])CC[C@]4([H])[C@@](CC[C@H](O)C4(C)C)(O)CC3=CC[C@@]21C)=O)=C

선적

Room temperature in continental US; may vary elsewhere.

보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Zhang CY, et al. Cytotoxic Activities of 9,10-seco-Cycloartane-Type Triterpenoids from the Chinese Liverwort Lepidozia reptans. J Nat Prod. 2021 Nov 19. [Content Brief]

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lepidozin G2869125-43-7ApoptosisInhibitorinhibitorinhibit

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Lepidozin G

Lepidozin G Related Antibodies

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