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  4. Leukotriene A4 methyl ester

Leukotriene A4 methyl ester  (Synonyms: LTA4 methyl ester)

製品番号: HY-112621
COA 取扱説明書 Technical Support

Leukotriene A4 methyl ester (LTA4 methyl ester) is synthesized in mast cells, eosinophils, and neutrophils from arachidonic acid by 5-lipoxygenase (5-LO), which exhibits both lipoxygenase and LTA4 synthase activities. LTA4 is rapidly metabolized by LTA4 hydrolase or LTC4 synthase to LTB4 or LTC4, respectively. LTA4, from leukocytes, is known to undergo transcellular metabolism in platelets, erythrocytes, and endothelial cells. Further metabolism of LTA4 by 15-LO leads to lipoxin biosynthesis. LTA4 as a free acid is highly unstable. The methyl ester is stable and can be readily hydrolyzed to the free acid as needed.

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Leukotriene A4 methyl ester

Leukotriene A4 methyl ester 構造式

CAS 番号 : 73466-12-3

容量 価格（税別） 在庫状況 数量
Solvent
25 μg (300.77 μM * 250 μL in Hexane containing 1% triethylamine) USD 330 お問い合わせ 2 - 3 weeks 4 - 5 weeks 5 - 6 weeks 1 - 2 weeks
Solvent
50 μg (300.77 μM * 500 μL in Hexane containing 1% triethylamine) USD 603 お問い合わせ 2 - 3 weeks 4 - 5 weeks 5 - 6 weeks 1 - 2 weeks

* アイテムを追加する前、数量をご選択ください

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Leukotriene A4 methyl ester 関連抗体

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製品説明

Leukotriene A4 methyl ester (LTA4 methyl ester) is synthesized in mast cells, eosinophils, and neutrophils from arachidonic acid by 5-lipoxygenase (5-LO), which exhibits both lipoxygenase and LTA4 synthase activities. LTA4 is rapidly metabolized by LTA4 hydrolase or LTC4 synthase to LTB4 or LTC4, respectively. LTA4, from leukocytes, is known to undergo transcellular metabolism in platelets, erythrocytes, and endothelial cells. Further metabolism of LTA4 by 15-LO leads to lipoxin biosynthesis. LTA4 as a free acid is highly unstable. The methyl ester is stable and can be readily hydrolyzed to the free acid as needed.

分子量

332.48

分子式

C21H32O3
CAS 番号
Appearance

Liquid

Color

Colorless to light yellow

SMILES

O=C(OC)CCC[C@@H]1O[C@H]1/C=C/C=C/C=C\C/C=C\CCCCC
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Solution, -20°C, 2 years
純度とドキュメンテーション
参考文献
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Leukotriene A4 methyl ester Related Classifications

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Keywords:

Leukotriene A4 methyl ester73466-12-3LTA4 methyl esterBiochemical Assay ReagentsInhibitorinhibitorinhibit

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製品名:
Leukotriene A4 methyl ester
製品番号:
HY-112621
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