Isotope-Labeled Compounds

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Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.

MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds (12461):

Cat. No.	Product Name	CAS No.	Purity	Chemical Structure

HY-N9596S

Stigmasta-4,22-dien-3-one-d5		98%
Stigmasta-4,22-dien-3-one-d₅ is the deuterium labeled Stigmasta-4,22-dien-3-one (HY-N9596). Stigmasta-4,22-dien-3-one is an antitubercular agent. Stigmasta-4,22-dien-3-one shows cytotoxicity against human HT1080 tumoral cell line with an IC₅₀ of 0.3 mM.

HY-P0059S

Teriparatide-d10
Teriparatide-d₁₀ (Human parathyroid hormone-(1-34)-d₁₀) is the deuterium labeled Teriparatide (HY-P0059). Teriparatide (Human parathyroid hormone-(1-34)) is a PTH1 receptor agonist. Teriparatide (Human parathyroid hormone-(1-34)) can be used for osteoporosis research.

HY-P0073S

Tyr-Gly-Gly-{Phe-13C9,15N}-Met-OH TFA		98%
Tyr-Gly-Gly-{Phe-¹³C₉,¹⁵N}-Met-OH TFA (Met-Enkephalin-¹³C₉,¹⁵N TFA) is the ¹³C- and ¹⁵N-labeled Tyr-Gly-Gly-Phe-Met-OH TFA. Tyr-Gly-Gly-Phe-Met-OH regulates human immune function and inhibits tumor growth via binding to the opioid receptor.

HY-P0206S

RPPGFSPF-(Arg-13C6,15N) TFA		98%
RPPGFSPF-(Arg-¹³C₆,¹⁵N) TFA is the ¹³C- and ¹⁵N-labeled RPPGFSPF.

HY-P0210S

DAMGO-d2
DAMGO-d₂ is the deuterium labeled DAMGO (HY-P0210). DAMGO is a μ-opioid receptor (μ-OPR ) selective agonist with a K_d of 3.46 nM for native μ-OPR.

HY-P10324

TAT-p16		98%
TAT-p16 (p16INK4a peptide) is a peptide mimic of p16INK4a that can induce an early G phase cell cycle arrest in the absence of active cyclin E:Cdk2 complex.

HY-P1142S

GLP-2(rat) (Ala-13C3,15N)		98%
GLP-2(rat) (Ala-¹³C3,¹⁵N) is ¹³C and ¹⁵N labeled GLP-2(rat) (HY-P1142). GLP-2(rat) is an intestinal growth factor. GLP-2(rat) stimulates cell proliferation and inhibits apoptosis. GLP-2(rat) enhances mucosal mass and function in residual small intestine after massive small bowel resection (MSBR).

HY-P11431

Cyclo(Gly-Pro)	97011-16-0	98%
Cyclo(Gly-Pro) is a cyclic dipeptide. Cyclo(Gly-Pro) can be derived from the Nterminus of the IGF-1. Cyclo(Gly-Pro) attenuates nociceptive behaviour and inflammatory response in mice.

HY-P1363S

β-Amyloid-15N (1-42), human TFA		98%
β-Amyloid-¹⁵N (1-42), human (TFA) is the ¹⁵N-labledβ-Amyloid (1-42) (TFA). β-Amyloid (1-42), human TFA (Amyloid β-Peptide (1-42) (human) TFA) is a 42-amino acid peptide which plays a key role in the pathogenesis of Alzheimer disease.

HY-P1389S

Neuropeptide S (human)-13C2,15N
Neuropeptide S (human)-¹³C₂,¹⁵N is the ¹³C- and ¹⁵N-labeled Neuropeptide S (human) (HY-P1389). Neuropeptide S human, a neuropeptide, is a potent cognate neuropeptide S receptor (NPSR) agonist. Neuropeptide S human can be used for Alzheimer's disease (AD) research.

HY-P2123S

Colistin A-d7 TFA		98%
Colistin A-d₇ TFA is the deuterium labeled Colistin A.

HY-P2625S

GLP-2(3-33) (Leu-13C6,15N)		98%
GLP-2(3-33) (Leu-¹³C₆,¹⁵N) is ¹³C and ¹⁵N labeled GLP-2(3-33) (HY-P2625). GLP-2(3-33), generated naturally by dipeptidylpeptidase IV (DPPIV), acts as a partial agonist on GLP-2 receptor (EC₅₀=5.8 nM).

HY-P3494S

Hepcidin-25-13C18,15N3 (human) TFA
Hepcidin-25-¹³C₁₈,¹⁵N₃ (human) TFA is the ¹³C- and ¹⁵N-labeled Hepcidin (human) TFA.

HY-P4473S

H-Phe-Ile-OH-13C6,15N TFA
H-Phe-Ile-OH-¹³C₆,¹⁵N TFA is the ¹³C- and ¹⁵N-labeled H-Phe-Ile-OH (HY-P4473). H-Phe-Ile-OH is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development.

HY-P4596S

H-Gly-Arg-OH (Arg-13C6,15N4)		98%
H-Gly-Arg-OH (Arg-¹³C₆,¹⁵N₄) is the deuterium labeled H-Gly-Arg-OH (HY-P4596).

HY-P5190S

RQIK-(Lys-fructosyl)-QTA-(Leu-13C6,15N)-VE		98%
RQIK-(Lys-fructosyl)-QTA-(Leu-¹³C₆,¹⁵N)-VE is the ¹³C and ¹⁵N labeled compound.

HY-P5201S

VTSEGAGLQLQK-13C6,15N2		98%
VTSEGAGLQLQK-13C6,15N2 is the 13C and 15N labeled VTSEGAGLQLQK. VTSEGAGLQLQK is an amino acid sequence in the C-terminal region of recombinant human alpha-acid glucosidase (rhGAA). VTSEGAGLQLQK can be used to bind anti-drug antibodies (ADA) in plasma and quantitatively analyze the therapeutic effect.

HY-P5537S

ETTVFENLPEK-13C11,15N2 TFA		98%
ETTVFENLPEK-¹³C₁₁,¹⁵N₂ (TFA) (ETTVFENLPEK-¹³C₁₁,¹⁵N₂ (TFA)) is a ¹³C- and ¹⁵N-labeled compound.

HY-P5538S

EPYFGYSGAFK-13C9,15N3 TFA		98%
EPYFGYSGAFK-¹³C₉,¹⁵N₃ (TFA) (EPYFGYSGAFK-¹³C₉,¹⁵N₃ (TFA)) is a ¹³C- and ¹⁵N-labeled compound.

HY-P6421S

LGPLVEQG-Arg(13C6,15N4) TFA		98%
LGPLVEQG-Arg(¹³C₆, ¹⁵N₄) TFA is a peptide containing ¹³C₆ and ¹⁵N₄ labeled Arg.

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