2. Academic Validation
  3. Anti-emetic principles of Pogostemon cablin (Blanco) Benth

Anti-emetic principles of Pogostemon cablin (Blanco) Benth

  • Phytomedicine. 1999 May;6(2):89-93. doi: 10.1016/S0944-7113(99)80041-5.
Y Yang 1,  K Kinoshita,  K Koyama,  K Takahashi,  T Tai,  Y Nunoura,  K Watanabe
Affiliations

Affiliation

  • 1 Department of Pharmacognosy and Phytochemistry, Meiji Pharmaceutical University, Tokyo, Japan.
PMID: 10374246 DOI: 10.1016/S0944-7113(99)80041-5
Abstract

Bioassay-guided fractionation of anti-emetic extracts and constituents of 8 traditional Chinese herbal drugs was performed. Twenty extracts described in Table 1 showed anti-emetic activity on copper sulfate induced-emesis in young chicks. From the n-hexane extract of Pogostemon cablin, patchouli alcohol (1), pogostol (2), stigmast-4-en-3-one (3), retusin (4), and pachypodol (5) were tested and exhibited anti-emetic effects.

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