1. Academic Validation
  2. 1-(1-Naphthyl)piperazine as a novel template for 5-HT6 serotonin receptor ligands

1-(1-Naphthyl)piperazine as a novel template for 5-HT6 serotonin receptor ligands

  • Bioorg Med Chem Lett. 2005 Mar 15;15(6):1707-11. doi: 10.1016/j.bmcl.2005.01.031.
Mase Lee 1 Jagadeesh B Rangisetty Manik R Pullagurla Małgorzata Dukat Vince Setola Bryan L Roth Richard A Glennon
Affiliations

Affiliation

  • 1 Department of Medicinal Chemistry, School of Pharmacy, Virginia Commonwealth University, Richmond, VA 23298-0540, USA.
Abstract

4-Sulfonyl analogs of 1-(1-naphthyl)piperazine bind at human 5-HT6 receptors and represent a novel class of human 5-HT6 receptor ligands.

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